CONFIRM anti-CD3 (2GV6) Rabbit Monoclonal Primary Antibody (CONFIRM anti-CD3 (2GV6) antibody) is a rabbit monoclonal antibody (IgG) directed against the nonglycosylated epsilon chain of the human CD3 molecule.1 CONFIRM anti-CD3 (2GV6) antibody is intended for use to qualitatively identify T cells by light microscopy in sections of formalinfixed, paraffin-embedded tissue on a VENTANA BenchMark IHC/ISH series of automated instruments.
This product should be interpreted by a qualified pathologist in conjunction with histological examination, relevant clinical information, and proper controls.
This antibody is intended for in vitro diagnostic (IVD) use.
- Matter M, Schwarz E, Marafioti T, Rechsteiner MP, Moch H. Immunohistochemical detection of CD3 in T-cell lymphomas: superior sensitivity of rabbit monoclonal 2GV6 antibody compared to mouse monoclonal F7·2·38 antibody. J Histotechnol. 2014;37(1),21-25.
- Lanier LL, Chang C, Spits H, Phillips JH. Expression of cytoplasmic CD3 epsilon proteins in activated human adult natural killer (NK) cells and CD3 gamma, delta, epsilon complexes in fetal NK cells. Implications for the relationship of NK and T lymphocytes. J Immunolol. 1992,149(6),1876-80.
- Carson F, Hladik C. Histotechnology: A Self Instructional Text, 3rd edition. Hong Kong: American Society for Clinical Pathology Press; 2009.
- Roche PC, Hsi ED. Immunohistochemistry-Principles and Advances. Manual of Clinical Laboratory Immunology, 6th edition. (NR Rose Ed.) ASM Press, 2002.