Infographic: Understanding BRAF and its role in melanoma

About half of all melanomas have BRAF gene mutations that drive rapid tumor growth1


Melanoma accounts for less than one percent of skin cancer cases, but the vast majority of skin cancer deaths.2 Although recreational exposure to the sun and a history of sunburn are major predisposing factors, detecting mutations in the BRAF gene can play an important role in guiding treatment options.

In 2011, Roche became the first company to receive simultaneous approval for a companion diagnostic and a therapy for BRAF - mutation positive advanced melanoma.

Infographic - Understanding BRAF and its role in melanoma


  1. Ascierto PA et al. The role of BRAF V600 mutation in melanoma. Journal of Translational Medicine. 2012;1085. doi10.11861479-5876-10-85
  2. Rogers HW, Weinstock MA, Feldman SR, Coldiron BM. Incidence estimate of nonmelanoma skin cancer (keratinocyte carcinomas) in the US population, 2012. JAMA Dermatol. 2015; 151(10):1081-1086.