Symptoms of COVID-19 and influenza may look similar1. Providing access to reliable and efficient testing on the fully-automated cobas® 6800/8800 Systems can help guide treatment decisions and prevent further disease transmission.
Both SARS-CoV-2 and influenza infections can present with similar symptoms, but treatment directions are likely to be different1. Knowing what infection a patient has will allow the clinician to optimally guide triage and treatment decisions, and bring confidence to patients.
The cobas® SARS-CoV-2 & Influenza A/B Test is a multiplex reverse transcription polymerase chain reaction (RT-PCR) assay intended for simultaneous qualitative detection and differentiation of SARS-CoV-2, influenza A virus, and/or influenza B virus in nasal or nasopharyngeal swab samples collected from individuals suspected of a respiratory viral infection consistent with COVID-19 by their healthcare provider.
Provide accurate diagnosis of SARS-CoV-2 or Influenza A/B infection for proper patient management.
Offer reliable and affordable testing to reduce further virus spreading after close contact with infected individuals.
Leverage high-volume cobas® 6800/8800 Systems and broad menu to expand COVID-19 testing solutions.
Test performanceView Full Table
|TARGET||POSITIVE AGREEMENT||NEGATIVE AGREEMENT||LoD (95% Probit)c|
0.0063 TCID50/mL (SARS-CoV-2)b
0.0082 TCID50/mL (pan-Sarbecovirus)b
|Influenza A**||100%||99.6%||0.086 TCID50/mL|
|Influenza B**||100%||99.7%||0.026 TCID50/mL|
a discordant results for SARS-CoV-2 are from samples of recovery/convalescent patients with decreasing viral loads close to or below the LOD of both tests
b one TCID50/mL is equal to 7,393 genome equivalents by ddPCR (per vendor’s Certificate of Analysis, USA-WA1/2020, infectious culture, Cat No NR-52281, Lot 70033175)
c based on co-formulated, combined lot performance
Key parametersView Full Table
|Targets||SARS-CoV-2, pan-Sarbecovirus, Influenza A, Influenza B|
Nasopharyngeal swab samples collected in the Copan UTM-RT System or the BD UVT System
Nasal swab samples collected in the Copan UTM-RT System, the BD UVT System, the cobas® PCR media, and 0.9% physiological saline
|Minimum amount of sample required||0.6 µL|
|Sample processing volume||0.4 µL|
|Test duration||Results are available within less than 3.5 hours after loading the sample on the system|
|System software||Runs with SW versions 1.2, 1.3, and 1.4|
|Size and open kit stability||384 tests; 90 days with 40 re-uses|