β-Amyloid (1-42) peptide deposition in the brain is one of the two hallmarks of Alzheimer’s disease (AD), besides neurofibrillary tangles. Pathological changes in the β-Amyloid (1-42) metabolism are the earliest alterations during AD development. These changes are reflected by the decrease in the CSF concentrations of β-Amyloid (1-42) as well as by the increase in the brain uptake of the specific tracers on the β-Amyloid (1-42) Positron Emission Tomography (PET).1
Elecsys β-Amyloid (1-42) CSF (Abeta42) is an in vitro diagnostic immunoassay intended for the quantitative determination of the β-amyloid (1-42) protein concentration in human CSF.
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