Elecsys^® β-Amyloid(1-42) CSF

β-Amyloid (1-42) peptide deposition in the brain is one of the two hallmarks of Alzheimer’s disease (AD), besides neurofibrillary tangles. Pathological changes in the β-Amyloid (1-42) metabolism are the earliest alterations during AD development. These changes are reflected by the decrease in the CSF concentrations of β-Amyloid (1-42) as well as by the increase in the brain uptake of the specific tracers on the β-Amyloid (1-42) Positron Emission Tomography (PET).¹

Elecsys β-Amyloid (1-42) CSF (Abeta42) is an in vitro diagnostic immunoassay intended for the quantitative determination of the β-amyloid (1-42) protein concentration in human CSF.

Platform availability

cobas e 601, cobas e 602

References

1. Lewczuk, P. et al. (2015). Advances in Medical Sciences 60, 76-82