Elecsys® Vitamin D total II

Allowing optimised patient care with results you can trust

Elecsys® Vitamin D total II

Allowing optimised patient care with results you can trust

Vitamin D has a proven impact on bone mineral density1. Desirable levels of 30 ng/mL have been shown to ­reduce the risk of falls2 and fractures3.

There is also growing scientific evidence linking the level of vitamin D (25-OH) to an increased risk of other indications such as diabetes, cardiovascular diseases, autoimmune diseases and different forms of cancer.4 The Elecsys® Vitamin D total II assay aids in the assessment of vitamin D sufficiency.

 

Benefits5

 

  • Direct traceability to the official reference measurement procedure (Ghent University ID-LC-MS/MS) for confidence in ­patient results
  • High lot-to-lot consistency for optimal therapy monitoring
  • Excellent functional sensitivity and high precision over the clinically relevant range
  • Efficiency due to consolidation of Vitamin D total, b-CrossLaps, P1NP, Osteocalcin and PTH testing on one fully automated platform
Elecsys® Vitamin D total II

Elecsys® Vitamin D total II

  • Assay time

    27 min

  • Sample material

    Serum and plasma

  • Sample volume

    12 µL

  • Limit of quantitation

    ≤5 ng/mL (≤12.5 nmol/L)

  • Repeatability

    <20 ng/mL SD ≤1.1 ng/mL; >20 ng/mL CV ≤5.5 %

  • Intermediate precision

    <20 ng/mL SD ≤1.4 ng/mL; >20 ng/mL CV ≤7.0 %

References

 

  1. Kuchukk NO, van Schoor NM, Pluijm SM, et al. Vitamin D status, parathyroid function, bone turnover, and BMD in postmenopausal women with osteoporosis: global perspective. J Bone Miner Res 2009;24:693-701.
  2. Bischoff-Ferrari, Heike A., et al. "Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials." Bmj 339 (2009): b3692.
  3. Bischoff-Ferrari, Heike A., et al. "Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials." Archives of internal medicine 169.6 (2009): 551-561.
  4. Holick MF. Vitamin D deficiency. N Engl J Med 2007;357:266-281.
  5. Roche Diagnostics, Method Sheet Elecsys® Vitamin D total II, 2018