Supports the creation of sample pools for use with the cobas® 6800/8800 Systems

The cobas p 680 instrument automates the creation of pools in secondary tubes and pipetting of samples into aliquot plates for archiving. From a deck capacity of 500 tubes, primary pools of 1, 6, 24, 96 and 480 may be created. The instrument utilises Roche standard 5-position racks and rack trays to help streamline workflow with Roche pre-analytics and analytic systems.

The cobas p 680 instrument combines proprietary pipette tip technology and liquid level monitoring to ensure reliable sample transfer during pooling.

Connect up to four cobas p 680 instruments to the cobas® 6800/8800 Systems to meet your lab’s needs.

Improved workflow efficiencies

  • Automated loading of racks onto instrument, once rack tray is deposited.
  • Error lane allows user to easily identify tubes with pipetting errors.

Confidence in full traceability

  • Full integration in the cobas 6800/8800 Systems software ensures full traceability of sample pool creation to final result.
  • Secondary tubes are barcoded for improved workflow efficiency and full traceability.

Flexible Pool Creation

  • Creation of pools with fewer samples than the configured pool size (e.g. creation of a pool of six with five samples); additional aliquots will be taken from samples to complete the pool. Aliquot plates may be created offline for sample archiving.


  • Total aspiration and dispense monitoring (TADM) of the pressure within the pipette tip during the pipetting process ensures accurate sample transfer.

Liquid level detection

  • Capacitive liquid level detection monitors the level of sample in a tube or plate to prevent overflow and carryover contamination during pipetting.

CO-RE tip technology

  • Compressed O-ring expansion (CO-RE) tip technology locks pipette tips in place with an expanding O-ring. The tip is released when the O-ring gently decompresses, preventing the creation aerosols to minimise contamination. Disposable filter tips are utilized to prevent cross-contamination.