Histotechnologist and Laboratory personnel training program for INFORM HER2 Dual ISH DNA Probe Cocktail

The course is designed for Histotechnologist and other Laboratory users to provide information about the processing and management of the HER2 Dual ISH DNA Probe Cocktail. HER2 Dual ISH DNA Probe Cocktail is designed to determine HER2 gene status by enumeration of the ratio of the HER2 gene to Chromosome 17. Histotechnologist and other professional users can randomly navigate any module within the five part training program. A certificate of completion is offered to those who complete each training module

Courses in this Series




  • Discuss the importance of determining HER2 gene status in breast cancer
  • List assay components
  • Review and understand the intended use
  • Describe how to assay works



  • Define pre-analytical factors that may affect the quality of assay results


Automated Staining Procedure


  • Describe the instrument setup
  • Describe the protocol selection process
  • Describe the automation procedure


Interpretation and Enumeration


  • Explain microscope optimisation
  • Define the best microscope objectives for slide interpretation
  • Define criteria of an acceptable slide
  • Identify an acceptable target area to enumerate



  • Describe suboptimal staining results
  • Describe suggested ways to mitigate suboptimal staining