This antibody is intended for in vitro diagnostic (IVD) use. Ventana Medical Systems' (Ventana) CONFIRM anti-Cytokeratin 20 (SP33) Rabbit Monoclonal Primary Antibody (CONFIRM anti-Cytokeratin 20 antibody) is directed against a type I cytokeratin protein of mature enterocytes and goblet cells of the gastric and intestinal mucosa. This antibody produces a cytoplasmic staining pattern, and may be used to aid in the identification of normal cytokeratin 20 expressing cells and neoplastic cells of colonic epithelial lineage. The antibody is intended for qualitative staining in sections of formalin-fixed, paraffin-embedded tissue.
The clinical interpretation of any staining, or the absence of staining, must be complemented by histological studies and evaluation of proper controls. Evaluation must be made by a qualified pathologist within the context of the patient’s clinical history and other diagnostic tests.