cobas® 4800 system

Innovation made simple

 

The cobas® 4800 system features state-of-the-art, fully automated sample preparation combined with real-time polymerase chain reaction (PCR) technology for amplification and detection of nucleic acid, plus easy-to-use software that seamlessly integrates both components. This combination of elements provides true walk-away automation for maximum lab efficiency.

It consists of the cobas x 480 instrument for the nucleic acid extraction sample preparation and PCR pipetting and the cobas z 480 real-time PCR analyzer.

 

The cobas z 480 analyzer is also available as single system and can be used for parameters in the oncology field like BRAF, KRAS and EGFR.

cobas x 480 instrument

  • Fully automated sample preparation from primary vials
  • Ready-to-use, load-and-go reagents
  • No thawing or mixing required
  • Less than 20-minute set-up for full run of 94 samples

cobas z 480 analyzer

  • Real-time PCR with digital data capture provides accurate qualitative results with no grey zone
  • Eliminates the need for equivocal sample retesting
  • Advanced results algorithm eliminates the need for manual curve analysis
     
Dependable performance, dependable results.

For reliable real-time PCR for medium- to high-throughput labs, the cobas® 4800 system was engineered to inspire confidence. It uses the latest generation of LightCycler Technology to deliver reproducible results and represents a new standard in innovation.

CO-RE tip technology

Improves sealing by securely locking pipette tips in place with an O-ring that expands smoothly to fit a specially designed groove. This O-ring gently decompresses during tip release to avoid motions that can create sample/reagent aerosols that lead to cross-contamination.

A proprietary Total Aspirate and Dispense Monitoring (TADM) system

Ensures valid results by monitoring the pressure within tips to detect low volumes and clogs; pressure responses that fall outside the expected range are reported as errors.

Five optical channels

To detect multiple targets from one reaction tube.

Designed for bi-directional LIS communication

To simplify test ordering while supporting integrity of results (no manual data entry required).

Includes remote diagnostics support

Through a secure web connection, our Service and Technical Support team can streamline troubleshooting and minimize downtime.

 

1) Simplifies workflow efficiency.

Streamlined design helps save time and resources because:

It requires less hands-on time than most comparable systems and needs minimal daily maintenance. The cobas® 4800 system enables and frees staff to spend more time on other critical tasks.

It accommodates multiple sample types and flexible batch sizes and provides an easy-to-use software interface that can make operation simple even for lab techs with no molecular diagnostics experience.

Roche assays for the cobas® 4800 system help deliver consistently reliable results because:

  • The proprietary AmpErase enzyme destroys virtually all previously generated amplicon to reduce cross-contamination concerns that can lead to false-positive results.
  • Automatic internal controls minimize the potential for false-negative results.

Each test is automatically analyzed with a unique kinetic algorithm so results are clearly positive, negative or invalid.

The cobas® 4800 system delivers fast results to help meet demanding turnaround times:

  • Requires < 40 minutes of hands-on time (96 sample run).
  • Reagents are ready to go, no preparation required.

The cobas® 4800 system features primary tube loading to eliminate manual sample transfer steps.

The cobas® 4800 system enables flexible ordering for an expanding, diverse menu of individual, combination or laboratory-developed tests.

 

2) Innovation that gets down to business.

cobas z 480

Position your lab for the future—today

Because it provides trustworthy results for high-volumn tests — while meeting the most demanding expectations for turnaround time — the cobas® 4800 system helps you meet your:

  • Operational goal (more test results/day with less downtime)
  • Clinical goals (fast, reliable results to support therapy decisions)
  • Financial goals (streamlined test requisition/cost-capture and minimum reliance on outside lab services)

Reliable results:

  • Proprietary kinetic algorithm software provides clear and precise answers
  • Reducing the need for retesting or interpretation

Efficiency:

  • By fully automated sample preparation and PCR set-up (for HPV, Virology, and CT/NG)
  • By bi-directional connectivity with your LIS for automated results reporting

Flexibility:

  • Option to use multiple primary vial types
  • User-defined workflow software for free programmable PCR applications

Load-and-go reagents:

  • Save time and labour
  • Low daily maintenance requirements
  • Processes up to 376 samples in 10 hours
  • Bi-directional connectivity to LIS
  • Easy to use software
  • Automated result interpretation

Genomics/Oncology

  • cobas® 4800 BRAF V600 Mutation Test
  • cobas EGFR Mutation Test

Infectious Disease

  • Cobas HPV Test

Microbiology

  • cobas Cdiff Test
  • cobas MRSA/SA Test

Virology

  • cobas HPV Test
  • cobas HSV 1 and 2 Test

Women's Health

  • cobas CT/NG v2.0 Test
  • cobas HPV Test
  • cobas HSV 1 and 2 Test
     

Bigger lab ?

Learn more about the cobas® 6800/8800 system

 

Molecular Lab

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cobas p 480 instrument
 
 
MagNa Pure System Family
 
 
 
qPCR Instruments
 
 
 
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