cobas h 232 POC system

 

Portable and easy-to-use, the cobas h 232 system helps frontline healthcare providers to quickly make a confident decision whether to admit, discharge or transfer a patient presenting with acute chest pain, dyspnea or other symptoms suggestive of acute cardiovascular disease. In addition, the enhanced cobas h 232 system now features wireless connectivity for immediate, streamlined data sharing*.

Thanks to its compact design, the cobas h 232 can easily be deployed near the POC patient where space is tight and mobile use is required, such as ambulances, general practitioner's office, emergency room (ER), or a designated lab area

Fast and reliable patient stratification:

  • Flexible: Suitable for use in pre-hospital settings and ER for early triage of patients.
  • Ready-to-use: Requires no sample preparation or lengthy setup procedures.
  • Reliable: Results comparable to Roche laboratory methods available in maximum 12 minutes.

Safety:

  • Operator ID entry and lockout to ensure use by authorized staff.
  • Patient and user ID to ensure correct documentation of test results.
  • Quality control lockout.

Control and traceability:

  • Connection to the cobas® POC IT solution allows extension of the testing network and ensures control of operators and quality assurance from the central laboratory.
  • Automatic re-certification of operators through cobas academy to ensure use by trained operators only.

Wireless Connectivity*:

  • Built-in WiFi ensures full wireless management and remote control
  • Fast transfer of results as they go straight to patient's health record
  • Automated transmission of results reduces human errors and increases safety

Sample material:

  • Heparinized venous whole blood

Data management capabilities:

  • Complies with industry standard
  • Designed to connect with the cobas POC IT solution
  • Complete documentation of results including patient and operator identification

Roche CARDIAC® POC Troponin T (Troponin T assay)

Roche CARDIAC POC Troponin T test on the cobas h 232 POC system

Intended use

Quantitative immunological test for the detection of cardiac troponin T in heparinized venous blood for use with the cobas h 232 instrument. The test is intended as an early aid in the diagnosis of acute myocardial infarction and identification of patients with an elevated mortality risk.

  • Results in just 12 minutes
  • Allows for early detection of cTnT in the pre-hospital setting such as general practitioner’s office, ambulances as well as in the Emergency Department.
  • Results standardized with Elecsys® Troponin T high-sensitive (cTnT-hs) laboratory test in the range of 40 – 2000 ng/L, *

References

* The Roche CARDIAC POC Troponin T is standardized with Roche's Elecsys® Troponin T high-sensitive laboratory test that showed a 99th percentile upper reference limit of a healthy cohort of 14 ng / L.

 

Roche CARDIAC® T Quantitative (Troponin T assay)

This test supports the diagnosis of patients with suspected myocardial cell damage – in cases of acute coronary syndrome or acute myocardial infarction (AMI, heart attack) for example. It also helps determine infarction size and risk stratification of patients with unstable angina pectoris by detecting minimal damages to the myocardium.

  • Reaction time: 12 min
  • Measuring range: 50 - 2,000 ng/L (50-100 ng/L is semiquantitative range indicating result is between 50-100 ng/L)
  • Cut-off values:
     < 50 ng/L = Low risk
     50 - 100 ng/L = Medium risk
     >100 = High risk

 

Roche CARDIAC® proBNP (NT-proBNP assay)

This test aids in diagnosis of patients with suspected heart failure, the monitoring of patients with compensated left ventricular dysfunction and the risk stratification of patients with acute coronary syndromes.

  • Reaction time: 12 min
  • Measuring range: 60 – 9,000 pg/mL
  • Cut-off values:
    <125 pg/mL = Exclusion of Non-acute heart failure
    <300 pg/mL = Exclusion of acute heart failure
  • Consideration of age-stratified cut-points for diagnosis of:
 Patient age     NT-proBNP value    
 < 50 years  > 450 pg/mL
 50 - 70 years  > 900 pg/mL
 > 50 years  > 1,800 pg/mL

 

Roche CARDIAC® D-Dimer (D-Dimer assay)

D-dimer is a rapid and reliable exclusion test for suspected DVT or PE (used in conjunction with the pretest probability score).

  • Reaction time: 8 min
  • Measuring range: 0.1 - 4.0 µg/mL
  • Cut-off values:
    < 0.5 µg/mL– PE / DVT unlikely
    >0.5 μg / mL – PE / DVT cannot be ruled out

 

Roche CARDIAC® CK-MB (CK-MB assay)

This test is used to support the diagnosis of acute coronary syndrome and myocardial infarction and assessment of reinfarction

  • Reaction time: 12 min
  • Measuring range: 1.0 - 40.0 ng/mL
  • Cut-off values:
    Female: 4 ng/mL*
    Male: 7 ng/mL*

*At the 99th percentile of a reference population

 

Roche CARDIAC® M (Myoglobin assay)

An early marker of myocardial damage to assist in diagnosis of acute coronary syndrome and myocardial infarction

  • Reaction time: 8 min
  • Measuring range: 30 - 700 ng/mL
  • Cut-off values:
    Female: 7 - 64 ng/mL
    Male: 16 - 76 ng/mL

*available exclusively on the  cobas h 232 system full connectivity version