CoaguChek® XS Plus system

The smart way to test INR at the Point of Need

PT/INR Monitoring tailored to a healthcare professional’s needs. Healthcare professionals can now test patients’ PT/INR right in their practice instead of waiting for lab results.

All three CoaguChek® XS devices use the same testing technology.  So the CoaguChek® XS Plus and Pro produce results equivalent to those obtained with reference laboratory methods and also compare closely to the patient’s device, the CoaguChek® XS.

Accurate and flexible technology – a smart way to test

  • Accurate, precise results in about one minute
  • The only system to perform onboard quality control and patient tests in a single test chamber
  • Results unaffected by heparin at therapeutic  levels
  • INR corrected for hematocrit within specified range

Streamlined data management

  • Stores 2000 patient and 500 QC test results
  • Operator and QC lockout to ensure your policies are followed
  • Calibration via code chip
  • Stores lot data for up to 60 codes

Fast, reliable results

  • Accurate PT/INR results in one minute
  • Built-in quality control checks every strip automatically
  • Lab-equivalent accuracy precision 1

Simple fingerstick test

  • Most patients prefer having a small drop of blood (just 8 μL) taken from a fingerstick to having blood drawn from a vein3

Improved patient outcomes

  • Frequent testing allows side effects to be minimized and increases the time spent within the therapeutic range 2           

1 Kitchen, D.P., Munroe, S., Kitchen, S., Jennings, I., Woods, T.A.L., Walker, I.D. (2008). Results from the first year of an external quality assessment programme for the users of CoaguChek XS and CoaguChek XS Plus for monitoring INRs. British Journal of Haematology, Volume 141 Supplement 1: P188.

2 Heneghan, et. al (2006). Lancet, 367; 404-411.[1]

3 Woods, K., Douketis, J.D., Schnurr, T., Kinnon, K., Powers, P. et al. (2004). Patient preferences for capillary vs. venous INR determination in an anticoagulation clinic: a randomized controlled trial. Thromb Res 114(3), 161-165.

CoaguChek® XS Plus provides accuracy, ease of use plus data management for recording patient IDs

The CoaguChek® XS Plus instrument kit contains:

  • 1 CoaguChek® XS Plus instrument
  • 1 Handheld power supply unit
  • 1 printed manual in English

Additional required components are CoaguChek® XS PT Test strips (in a vial):

  • Box with 2 vials of 24 strips with a code chip
  • Box with 1 vial of 24 strips with a code chip

Optional accessories:

  • Handheld base unit kit: docking station (to reload the battery pack and transfer data to a computer)
  • Handheld battery pack: option instead of standard batteries or power supply (to gain flexibility)

Optional international 1 level CoaguChek® XS PT-control kit including:

  • 4 vials with a concentration of ~ 2.0 INR
  • 4 diluent-filled droppers
  • 1 code chip
  • Package insert

Detection system Amperometric (electrochemical) determination of the PT/INR after activation of the coagulation with human recombinant thromboplastin.

User interface Full graphical (TFT).

Support and safety functions QC lockout, Patient & User ID, protection with administrator ID Sample application Outside the meter, with top- and 2 sides (left or right)-dosing options.

Operating Conditions

  • Operating Temperature +15° C to +32 °C (59 °F to 90 °F)
  • Operating humidity and altitude 10 - 85% - 4300 m
  • Handling
  • - First option: Operate the monitor on a level surface, free of vibrations
    - Second option: hold the monitor in your hand, so that it is roughly horizontal

  • Measuring range INR: 0.8 - 8.0; %Q: 120 - 5; SEC: 9.6 - 96
  • Memory 2000 patient and 500 QC results with date and time.
  • 60 code chip records.
  • Operator lists with up to 5000 Operator IDs with corresponding 2nd ID.
  • Patient lists with up to 4000 Patient IDs with corresponding 2nd and 3rd IDs.
  • Interfaces Infrared interface
  • - Power supply adaptor: input: 100-240 V / 50-60Hz / 400 mA; output: 7.5 V DC/ 1.7 A
    - 4 x 1.5 V AA batteries (alkali-manganese)
    - Rechargeable battery pack (optional)

  • Number of tests per set of batteries Approx. 80 tests (approx. 60 tests per charging cycle if the rechargeable battery pack is used)
  • Dimensions 185 x 97 x 43 mm
  • Weight 311 g (without batteries)

Sample Material

  • Sample type Fresh capillary whole blood or non-anticoagulated venous whole blood
  • Sample size ≥ 8 µl
  • Interferences Refer to the test strip package insert

Test Strips

  • ISI Approx. 1.0
  • Sensitivity to heparin Not at therapeutic levels, up to 0.8 I.U/ml for UFH and to 2 anti-Xa.U/ml for LMWH
  • Quality control On each strip, through the same channel as the blood passes
  • Stability 21 months from production (+ 2° C to + 30° C)