cobas^® KRAS Mutation Test

The cobas^® KRAS Mutation Test offers broad mutation coverage of KRAS codons 12, 13 and 61 to identify colorectal cancer patients who are not likely to respond to anti-EGFR monoclonal antibody therapies.

• The cobas^® KRAS Mutation Test detects major mutations in codons 12, 13 and 61 from colorectal cancer patients
• In formalin-fixed, paraffin-embedded tissue (FFPET), the cobas^® KRAS Mutation Test can detect <5% mutant sequence copies in a background of wild-type DNA
• Robust, reliable KRAS test results can be obtained from a single, 5µm FFPET section with >10% tumor content using the cobas^® KRAS Mutation Test
• The test can be performed in <8 hours so results can be reported to the treating physician within a few days from laboratory receipt of specimen
• Liquid, ready-to-use reagents increase laboratory efficiency
• Automated result interpretation and test reporting provides consistent, objective and reproducible results from laboratory to laboratory