Products

Colorectal IHC portfolio

Deliver diagnostic confidence

Roche offers a robust menu of tools to aid in colorectal cancer diagnostics. The Roche portfolio of assays, including IHC diagnostic assays, deliver the high sensitivity and specificity pathology professionals need.

Fully-automated IHC/ISH staining

Roche antibodies are ready to use on the fully-automated VENTANA BenchMark IHC/ISH staining platforms, reducing the time-to-result and resources required with manual or semi-automated solutions.

VENTANA anti-MLH1 (M1) Mouse Monoclonal Primary Antibody
VENTANA anti-MLH1 (M1) Mouse Monoclonal Primary Antibody

MLH1 (M1) Mouse Monoclonal Primary Antibody is used to qualitatively identify human DNA mismatch repair (MMR) protein MLH1 within the context of an antibody panel. MLH1 is expressed in the nucleus of normal proliferating cells and loss of MLH1 is associated with colorectal and other cancers.

  • Mouse monoclonal antibody

  • Deficient or low levels of MLH1 are associated with risk for Lynch syndrome in colorectal and other cancers

  • Fully automated

VENTANA anti-PMS2 (A16-4) Mouse Monoclonal Primary Primary Antibody
VENTANA anti-PMS2 (A16-4) Mouse Monoclonal Primary Antibody
 

PMS2 (A16-4) Mouse Monoclonal Primary Antibody is used to qualitatively identify human DNA mismatch repair (MMR) protein PMS2 within the context of an antibody panel. PMS2 is expressed in the nucleus of normal proliferating cells and loss of PMS2 is associated with colorectal and other cancers.

  • Mouse monoclonal antibody

  • Deficient or low levels of PMS2 are associated with risk for Lynch syndrome in colorectal and other cancers

  • Fully automated

VENTANA anti-MSH2 (G219-1129) Mouse Monoclonal Primary Antibody
VENTANA anti-MSH2 (G219-1129) Mouse Monoclonal Primary Antibody
 

MSH2 (G219-1129) Mouse Monoclonal Primary Antibody is used to qualitatively identify human DNA mismatch repair (MMR) protein MSH2 within the context of an antibody panel. MSH2 is expressed in the nucleus of normal proliferating cells and loss of MSH2 is associated with colorectal and other cancers.

  • Mouse monoclonal antibody

  • Deficient or low levels of MSH2 are associated with risk for Lynch syndrome in colorectal and other cancers

  • Fully automated

VENTANA anti-MSH6 (SP93) Rabbit Monoclonal Primary Antibody
VENTANA anti-MSH6 (SP93) Rabbit Monoclonal Primary Antibody
 

MSH6 (SP93) Rabbit Monoclonal Primary Antibody is used to qualitatively identify human DNA mismatch repair (MMR) protein MSH6 within the context of an antibody panel. MSH6 is expressed in the nucleus of normal proliferating cells and loss of MSH6 is associated with colorectal and other cancers.

  • Mouse monoclonal antibody

  • Deficient or low levels of MSH6 are associated with risk for Lynch syndrome in colorectal and other cancers

  • Fully automated

BRAF V600E (VE1)
VENTANA anti-BRAF V600E (VE1) Mouse Monoclonal Primary Antibody
 

BRAF V600E (VE1) Mouse Monoclonal Primary Antibody may be used to aid in the identification of the mutant protein, BRAF V600E.

  • Mouse monoclonal antibody
  • Aids in the detection of the BRAF V600E mutant protein
  • Fully automated
CDX-2 (EPR2764Y)
CDX-2 (EPR2764Y)
 

CDX-2 (EPR2764Y) is a caudal-related homeobox transcription factor whose expression in the adult is normally restricted to the intestinal epithelium. Loss of CDX-2 protein expression has been correlated with loss of differentiation in colorectal cancers. Anti-CDX-2 antibody has been useful in distinguishing gastrointestinal origin of metastatic adenocarcinomas and carcinoids.

  • Rabbit monoclonal antibody
  • Loss of CDX-2 protein expression has been correlated with loss of differentiation in colorectal cancers
  • Aids in distinguishing gastrointestinal origin of metastatic adenocarcinomas and carcinoids
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