Take charge of antimicrobial prescribing with the cobas® Liat® PCR System

Antibiotics have transformed the practice of medicine, making once lethal infections readily treatable. However, the overuse or misuse of antibiotics has led to the rise of bacterial superbugs, which can be resistant to some forms of treatment. For antibiotics to remain effective, their use must be optimized.1

The cobas® Liat® PCR System brings laboratory-quality PCR technology right to the point of care, providing fast and accurate results you can trust across a growing number of respiratory infections.

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Diagnose confidently with the cobas® Liat® System

Most upper respiratory tract infections are caused by viruses, where antibiotics have no beneficial effect. Studies from general practice have demonstrated high rates of unnecessary antibiotic prescribing for patients with these types of infections.2

Together with assessment of signs and symptoms, testing before treatment is an important step in determining the appropriate course of action. While most testing options offer a tradeoff between speed and accuracy, the cobas® Liat® PCR System brings timely and reliable testing where it’s needed most: the point of care.

80-90-percent
Antibiotics used in medicine are largely prescribed by general practitioners.

Primary care accounts for 80–90% of all antibiotic prescriptions in Europe, and most are prescribed for respiratory tract infections.3

However, sometimes they are prescribed for conditions antibiotics cannot treat.

Of adults seeking treatment for respiratory infections in the US, a study found more than two thirds of antibiotics were most likely prescribed inappropriately.4

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45-percent
Antibiotic treatment is most effective when it's appropriate.

A study reports a 45% reduction in antibiotic prescribing in adults using rapid tests rather than signs and symptoms checks.5

Advanced diagnostics can help practitioners make informed  treatment decisions.
 

Increase diagnostic confidence with the cobas® Liat® PCR System—avoid the need for healthcare professionals to question a result, or for patients to wait for one. Avoid the need to question a result, wait for lab confirmations or rely solely on empiric treatment.

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Small, swift, simple, and secure

There is a need for quick, well-informed treatment decisions at the point of care. On-site rapid antigen tests may be fast, but also have a lower rate of accuracy and require confirmation in certain populations. Lab cultures are accurate, but have a long turnaround time—from 4 hours to 5 days.

The cobas® Liat® PCR System offers a unique combination of speed, sensitivity and specificity. With a growing number of assays featuring turnaround times of 20 minutes or less, this compact molecular solution supports effective clinical management.

 

Explore our expanding assay menu

Benchmark ULTRA system

cobas® Liat Strep A Assay

A real-time polymerase chain reaction (PCR) test for the detection of Strep A in throat swab specimens from patients with signs and symptoms of pharyngitis, cobas® Strep A delivers lab quality results in ~15 minutes.

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Ventana HE 600

cobas® Liat Influenza A/B Assay

Get the speed and reliability you need to support a timely, accurate diagnosis with the cobas® Influenza A/B assay. A multi-plex real-time PCR assay, cobas® Influenza A/B differentially detectes both influenza A and influenza B in ~20 minutes.

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VENTANA BenchMark Special Stains system

cobas® Liat Influenza A/B + RSV Assay

Timely results from cobas® Influenza A/B & RSV help guide clinical response for infection management and control. With extraordinary sensitivity, cobas Influenza A/B & RSV provides the reassurance needed when prescribing antiviral treatment. 

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Antimicrobial Stewardship: PCR Solution

Near-patient molecular testing can support antimicrobial stewardship efforts by allowing healthcare professionals to diagnose quickly and accurately right at the point of care. Take control of antimicrobial prescribing with the cobas® Liat® PCR System and make your next diagnosis with the confidence that comes with PCR where it’s needed most.

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References:

1. Ventola, CL. The Antibiotic Resistance Crisis: Part 1: Causes and Threats. P T. 2015 Apr;40(4):277–283. 
2. Bagger K, Nielsen AB, Siersma V, Bjerrum L. Inappropriate antibiotic prescribing and demand for antibiotics in patients with upper respiratory tract infections is hardly different in female versus male patients as seen in primary care. Eur J Gen Pract. 2015;21:118-123. doi: 10.3109/13814788.2014.1001361. 
3. Llor C, Bjerrum L. Antimicrobial resistance: risk associated with antibiotic overuse and initiatives to reduce the problem. Ther Adv Drug Saf. 2014;5(6):229–241. doi: 10.1177/2042098614554919. 
4. O’Neill J. Rapid Diagnostics: Stopping unnecessary use of antibiotics. Review on Antimicrobial Resistance. October 2015. 5. McIsaac WJ, Kellner JD, Aufricht P, Vanjaka A, Low DE. Empirical validation of guidelines for the management of pharyngitis in children and adults. JAMA. 2004;291:1587–1595.
5. Ventola CL-Pharmacy & Therapeutics-2015-Clinician Microbiology The Antibiotic Resistance Crisis: Part 1: Causes and Threats

*Turnaround time varies by assay: cobas® Influenza A/B, 20 minutes; cobas® Influenza A/B & RSV, 20 minutes; cobas® Strep A, 15 minutes.