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"", "StructureGroupName": "", "StructureNodeStatus": "invalid" } ] }, { "ProductID": "3.8.2.4.3.3", "BrandName": "MagNA Pure Sealing Foil", "ProductNameAddition": "", "ReferenceType": "Consumable", "Classification": [ { "IdentifierofStructureSystem": "OWP_Product_Types", "NameofStructureSystem": "Product Types", "StructureNodeID": "50-000-00", "StructureGroupPath": "Consumables", "StructureGroupName": "Consumables", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "Product_Grouping", "NameofStructureSystem": "Product Grouping", "StructureNodeID": "06-0057", "StructureGroupPath": "LifeScience->MagNA Pure LC 2.0 Accessories", "StructureGroupName": "MagNA Pure LC 2.0 Accessories", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "OWP_Family", "NameofStructureSystem": "Product Families", "StructureNodeID": "260", "StructureGroupPath": "MagNA Pure", "StructureGroupName": "MagNA Pure", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "Lab_Type", "NameofStructureSystem": "Lab Types", "StructureNodeID": "010-00", "StructureGroupPath": "Molecular Lab", "StructureGroupName": "Molecular Lab", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "Lab_Type", "NameofStructureSystem": "Lab Types", "StructureNodeID": "150-00", "StructureGroupPath": "Research Lab", "StructureGroupName": "Research Lab", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "Product_Solutions", "NameofStructureSystem": "Product Solutions", "StructureNodeID": "100", "StructureGroupPath": "Molecular", "StructureGroupName": "Molecular", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "Lab_Type", "NameofStructureSystem": "Lab Types", "StructureNodeID": "170-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Applications", "NameofStructureSystem": "Applications", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "OWP_Techniques", "NameofStructureSystem": "Techniques", "StructureNodeID": "999-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Disease_Areas", "NameofStructureSystem": "Disease Areas", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Pathogens", "NameofStructureSystem": "Pathogens", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Health_Topics", "NameofStructureSystem": "Health Topics", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" } ] }, { "ProductID": "3.8.2.4.3.1", "BrandName": "MagNA Pure Tip 1000μL", "ProductNameAddition": "", "ReferenceType": "Consumable", "Classification": [ { "IdentifierofStructureSystem": "Product_Grouping", "NameofStructureSystem": "Product Grouping", "StructureNodeID": "03-0703", "StructureGroupPath": "Molecular->MagNA Pure 96 Accessories and Consumables", "StructureGroupName": "MagNA Pure 96 Accessories and Consumables", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "OWP_Family", "NameofStructureSystem": "Product Families", "StructureNodeID": "260", "StructureGroupPath": "MagNA Pure", "StructureGroupName": "MagNA Pure", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "OWP_Product_Types", "NameofStructureSystem": "Product Types", "StructureNodeID": "50-000-00", "StructureGroupPath": "Consumables", "StructureGroupName": "Consumables", "StructureNodeStatus": "valid" }, { "IdentifierofStructureSystem": "Lab_Type", "NameofStructureSystem": "Lab Types", "StructureNodeID": "010-00", "StructureGroupPath": "Molecular Lab", "StructureGroupName": 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"StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Pathogens", "NameofStructureSystem": "Pathogens", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Health_Topics", "NameofStructureSystem": "Health Topics", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" } ] }, { "ProductID": "3.8.11.3.4.1", "BrandName": "Tip CORE TIPS with Filter, 50uL", "ProductNameAddition": "", "ReferenceType": "Consumable", "Classification": [ { "IdentifierofStructureSystem": "Product_Grouping", "NameofStructureSystem": "Product Grouping", "StructureNodeID": "06-0006", "StructureGroupPath": "LifeScience->FLOW System Accessories and Disposables", "StructureGroupName": "FLOW System Accessories and Disposables", "StructureNodeStatus": "valid" }, { 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"99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "OWP_Techniques", "NameofStructureSystem": "Techniques", "StructureNodeID": "999-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Disease_Areas", "NameofStructureSystem": "Disease Areas", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Pathogens", "NameofStructureSystem": "Pathogens", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "OWP_Family", "NameofStructureSystem": "Product Families", "StructureNodeID": "999", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" }, { "IdentifierofStructureSystem": "Health_Topics", "NameofStructureSystem": "Health Topics", "StructureNodeID": "99-00-00", "StructureGroupPath": "", "StructureGroupName": "", "StructureNodeStatus": "invalid" } ] } ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "en", "Value": "The MagNA Pure 24 System is an automated nucleic acid purification system consisting of the MagNA Pure 24 instrument, software, consumables and reagents. The MagNA Pure 24 System is intended for use by professional users for the purification of nucleic acids from biological samples for in vitro diagnostic purposes.", "Country": "XG", "Code": "Intended Use", "Name": "Intended Use" }, { "Language": "en", "Value": "About run types and workflows

The MagNA Pure 24 System offers 4 run types:

Purification (rack) run
In a purification (rack) run, the instrument pipettes sample material from sample tubes, processes it, and transfers the eluates to the output consumables in the cooling station.
The purification (rack) run is the fully automated combination of a sample transfer run and a purification (cartridge) run.

Purification (cartridge) run
In a purification (cartridge) run, the processing cartridges are pre-filled with sample material, either in a previous sample transfer run, or by manual pipetting. The instrument processes the sample material, and transfers the eluates to the output consumables in the cooling station.
In the case of a previous sample transfer run, open the corresponding order to load sample details.

Post elution run
In a post elution run, the instrument pipettes eluates into 8-tube strips (either empty or containing manually prepipetted PCR master mix reagent). From each eluate, the instrument pipettes up to 2 eluate aliquots. Additionally, the instrument pipettes controls. Sample information from a previous purification run is loaded when reading the barcodes of the eluate output consumables.
A post elution run uses the cooling station only and requires a dedicated post elution adapter.

Sample transfer run
In a sample transfer run, the instrument pipettes sample material from sample tubes into processing cartridges.
You can then use the sample-filled processing cartridges in a purification (cartridge) run.

The run types differ in input and output and use different instrument stations.(see Fig. 2).
 
", "Country": "XG", "Code": "Principle", "Name": "Principle" }, { "Language": "en", "Value": "For safety related information refer to the MagNA Pure 24 Safety Manual.

Chemical reaction producing toxic gas
Mixing bleach or DNA AWAY™ Surface Decontaminant with reagents can result in a chemical reaction that produces a highly toxic gas.
-> Do not allow reagents containing guanidine thiocyanate to contact sodium hypochlorite (bleach) solution or acids.
See also the reference from the FDA: Transport Media Safety Risk - Use Compatible Transport Media with SARS-CoV-2 Tests that Use Bleach - Letter to Clinical Laboratory Staff and Health Care Providers.", "Country": "XG", "Code": "Safety Information", "Name": "Safety Information" }, { "Language": "en", "Value": "The MagNA Pure 24 System is a fully automated clinical sample extractor. It extracts nucleic acids from various sample types, sample tubes, and volume inputs for multiple downstream applications.
The main features of the system are:

  • Scalable purification of 1 to 24 samples
  • Primary/secondary tube handling
  • Inventory and sample management via barcodes
  • Efficient order management via host
", "Country": "XG", "Code": "Product Description", "Name": "Product Description" }, { "Language": "en", "Value": "1. MagNA Pure 24 Instrument
2. Built-in control unit with preinstalled MagNA Pure 24 operating software and purification protocols
3. MagNA Pure 24 Accessories
4. Digital User Assistance", "Country": "XG", "Code": "Content", "Name": "Content" } ] } } ] }

MagNA Pure 24システム

Product image for MagNA Pure 24 System
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手間のかからない精製、自動化がもたらす信頼性

 
  • 再現性のある安定した産生を実現する実証済みの性能
  • 親検体の取り扱いで1~24検体のフレキシブルな抽出をわずか1時間強で実現
  • たった1種類の共通試薬のみで10種類のヒト検体タイプ、200 μL~4 mLのスタート検体量に対応
  • バーコードを用いたトラッキングシステムを介して、試薬消耗品の在庫と検体を追跡
  • 真のウォークアウェイタイムを提供
  • 内蔵UVランプおよびCO-REチップ技術によるコンタミネーション防止

 

充填済みですぐに使えるバーコード付き試薬キット

 

MagNA Pure 24システム用の共通トータル核酸キットは、不要な複雑性を排除し、たった1つの共通試薬キットを用いて、10種類のヒト検体から核酸を効率的に抽出することができます。試薬カセットを密閉して、別の日に再利用できます。搭載されたバーコードスキャニング機能で、試薬使用状況を確認、トラッキングします。

 

より多くのことを行う柔軟性

 

MagNA Pure 24システムは、たった1つの共通試薬キットで最大10種類の異なるヒト検体から核酸を抽出する柔軟性を提供します。この簡易化された試薬コンセプトを信頼し、最適化されたプロトコールか、あらかじめプログラム化されたプロトコールのいずれかを選択することで、1つのプロトコール内の混合バッチの検体タイプと主要チューブから核酸を抽出します。

 

プロトコールのダウンロード

 

MagNA Pure 24システムの新しいプロトコールをダウンロードいただけます。より詳細な情報は、ここをクリックしてください(注:米国ではダウンロードすることはできません)。

MagNa Pure 24チャート

効率化が容易に

MagNA Pure 24システムは自動化されているだけではありません。バーコードを用いた簡単なトラッキングと最小限のユーザー操作によって、MagNA Pure 24システムは真のウォークアウェイタイムを提供します。その結果人為的ミスが減少し、貴重な時間を節約することができます。

 

  • 簡単な抽出の設定
  • 搭載されたタッチスクリーンの直観的かつガイド付きのユーザーインターフェース
  • ファストプロトコールを用いて30分以内で最大8検体を精製
  • 実行前の充填チェックは30秒未満
  • 日々使用する前の迅速な機器の起動(5分未満)
  • LISとの接続を介した途切れのないデータ管理

 

組み込まれた信頼性

 

遺伝子検査に関しては、溶出液中の信頼性がすべてです。MagNA Pure 24システムは、IVD/CE-IVD装置であり、人為的ミスを低減しながら、溶出液の品質を保証するため、監視機能を備えています。

 

  • 汚染および安全性制御機能
  • 検体IDおよび試薬の使用状況を追跡するバーコーディング性能
  • 溶出液保存用クーリングブロック
  • 追跡を可能にする監査管理機能を用いたソフトウェア
  • パソコン上での独立したアーカイブビューアーを用いた保管データの閲覧

研究試薬

表の全てを見る

研究試薬

商品コード 製品名 包装 貯法
518-218522 MagNA Pure 24 Total NA Isolation Kit 最大96回 15~25℃
518-218539 MagNA Pure 24 MGP Set 12本 15~25℃
518-221768 MagNA Pure cfNA Buffer Set 最大96回 15~25℃
06640702001 MagNA Pure 96 DNA Tissue Lysis Buffer 100mL 15~25℃
03246779001 MagNA Pure LC Total Nucleic Acid Isolation Kit
- Lysis/Binding Buffer Refill
100mL 15~25℃
04659180001 MagNA Pure Bacteria Lysis Buffer 20mL 15~25℃
04805160001 MagNA Pure DNA Tissue Lysis Buffer 100mL 15~25℃
518-498979 S.T.A.R. Buffer 3×100mL 15~25℃

消耗品・その他

表の全てを見る

消耗品・その他

商品コード 製品名 包装 貯法
518-218546 MagNA Pure 24 Processing Cartridge 48個 15~25℃
518-218553 MagNA Pure 24 Processing Tip Park / Piercing Tool 48/50個 15~25℃
518-221744 MagNA Pure Tip 1000 μL 40×96個 15~25℃
518-218560 MagNA Pure 24 Piercing Tool 50個 15~25℃
518-221751 MagNA Pure Sealing Foil 100個 15~25℃
518-218591 MagNA Pure Tube 2.0 mL 350(10×35)個 15~25℃
518-218577 FrameStrip® with flat caps–Low profile 120チューブストリップ -20~60℃
518-218584 FrameStrip® with flat caps–High profile 120チューブストリップ -20~60℃
518-218508 Tip CORE TIPS with Filter, 50 μL 60×96個 15~40℃

概説

注文

技術文書

MagNA Pure 24 System protocols

The new MagNA Pure 24 System protocols package 3.0 are available for download from the table below (note: not available for download in the US).

 

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text
Target  Protocol name Input sample type and sample volumes
The latest version of MagNA Pure 24 protocols are available to download from the table below (not available in US)
 Elution volume  Run time♰ (h:mm)
 Whole blood  Plasma  Serum Nasal swabs*  BAL**
 Urine  Stool  Cultured cells Fresh-frozen tissue FFPET***
Bacterial, fungal and viral NA Pathogen 200  

Protocol optimized for speed

200 μL   50 or 100 μL 1:22
Fast Pathogen 200  

8 sample protocol optimized for speed, yield and purity

  0:35
Pathogen 1000

Protocol optimized for yield and purity

500 or 1000 μl   1:40
External Lysis Pathogen 200
External Lysis Pathogen 500  

Protocols optimized with external lysis buffer

450 μl lysate from 200 μl sample
1450 μl lysate from 500 μl sample
  1:30
1:40
Genomic DNA hgDNA 200  

Protocol optimized for human genomic NA

200 μl (≤ 2x106 cells)   Up to 5x105 Up to 5 mg   1:15
Fast hgDNA 200  

8 sample protocol optimized for speed

  0:25
hgDNA ds 200  

Protocol optimized for NGS

1:15
hgDNA 1000  

Protocol optimized for yield and purity

500 μl (≤ 5x106 cells)
1000 μl (≤ 1x107 cells)
100 or 200 μl 2:25
Up to 1x106
DNA FFPET 1000  

Deparaffinization and lysis on board

  Up to 6 x 5 μm sections (up to 6 mm3) 50 or 100 μl 5:30
Cell-free NA cfNA ss 2000
cfNA ss 4000  

Protocol optimized for single-stranded DNA

  2000 μL   50 or 100 μL 2:05
4000 μL 3:00
cfNA ds 2000
cfNA ds 4000  

Protocol optimized for double-stranded DNA

  2000 μL   100, 150 or 200 μL 2:30
4000 μL 3:30
cfNA ds 4000 hp  

Protocol optimized for double-stranded DNA and NGS

  4000 μL   60 or 150 μL 4:40
Post elution Sample Transfer   to the processing cartridge 200 μL
500 μL
1000 μL
  0.08
PCR Setup   for 2-25 μL per eluate for PCR Sstup in Frame-Strip with flat caps-Low Profile or LightCycler® 8-tube strips   0.05
Archiving   for 2-25 μL per eluate for PCR Sstup in FrameStrip low Profile strips or LightCycler® 8-tube strips 0.05
New Protocol
*Nasopharyngeal/nasal swabs
**BAL - Bronchoalveolar lavage
***FFPET - formalin-fixed paraffin-embedded tissue
♰These times are approximate and should only be used as a guidance.
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