Anti-PRAME (EPR20330) Rabbit Monoclonal Primary Antibody

H&E is the primary tool for diagnostic evaluation of potential melanocytic lesions. However, not all melanomas are easily diagnosed using H&E alone.

PRAME expression in formalin-fixed paraffin-embedded tissue is detected by immunohistochemistry and frequently demonstrates a diffuse nuclear immunostaining pattern in in situ and invasive melanoma. In contrast, the majority of benign melanocytic nevi lack nuclear PRAME staining.1

Diffuse PRAME expression in a melanoma can improve our confidence and diagnostic accuracy, and lead to more informed clinical decisions, and improved patient outcomes.

The PRAME (EPR20330) Antibody is the latest addition to Roche’s robust dermatology portfolio with more than 50 dermatology biomarkers designed to meet a broad range of diagnostic needs.