Precision Oncology Screening Platform Enabling Clinical Trials (PrOSPECT)

Media Release

Improving access to personalised healthcare and clinical trials for Australians living with cancer

Roche encourages greater participation in local oncology clinical trials and broader access to comprehensive genomic profiling through a new public-private partnership consortium with the Australian Government, research, academia and not-for-profit sectors.


SYDNEY, 17 March 2022 – Roche Australia, in partnership with the Australian Federal Government, Omico, and other partners, today announced an agreement to jointly fund an important new initiative aimed at improving access to clinical trials for Australians diagnosed with cancer. Through Precision Oncology Screening Platform Enabling Clinical Trials (PrOSPECT), thousands of eligible cancer patients are expected to gain access to comprehensive genomic profiling (CGP), enabling more efficient clinical trial screening and matching to the most appropriate trial.

As part of a $185 million project to establish Australia as a regional hub for the development of innovative medicines to treat cancer, the Federal Government has awarded Omico a $61.2 million grant to establish PrOSPECT. As a foundational partner in the PPP consortium, Roche has committed up to $20 million in funding for the project. The remaining funding will be contributed by the National Computational Infrastructure (NCI), the Children's Cancer Institute (CCI), Minderoo Foundation, and other project partners.

"Roche is incredibly proud to be a foundational partner for PrOSPECT," said Stuart Knight, General Manager of Roche Products. "We see this as an important opportunity to collaborate with the Government, Omico and other project partners, to build a robust and sustainable healthcare ecosystem that will enable broader access to comprehensive genomic profiling for Australian cancer patients, and support access to local clinical trials."

"By enabling broad access to comprehensive genomic profiling, PrOSPECT offers patients – particularly those with advanced or metastatic disease – the potential to receive targeted therapy as early as possible in their cancer journey, thereby improving their prognosis and treatment outcomes," said Mr Knight.

As one of the world's leading innovative pharmaceutical and diagnostic companies in oncology healthcare, Roche is uniquely positioned to realise the transformative potential of oncology personalised healthcare (PHC) – a strategy that aims to find the right treatment for each patient at the right time, based on the molecular biology of their specific tumours.

"Our combined strengths in diagnostic and pharmaceutical expertise, along with our leading portfolio of medicines, proven history of ground-breaking science, growing capabilities in data insights, and deep network of strategic partnerships, have made us a leader in personalised healthcare," said Allison Rossiter, Managing Director of Roche Diagnostics Australia.

"Personalised healthcare utilises more powerful diagnostic tools and more precise treatments by capitalising on our increasingly sophisticated understanding of differences among patients, diseases and medicines. By delivering care tailored to the individual, personalised healthcare can transform patients’ lives; helping to prevent, diagnose and treat patients more quickly and effectively," said Ms Rossiter.

Roche's investment in PrOSPECT follows its previous collaboration with the Australian Government, Omico, and other partners, on the ASPiRATION Study in 2020. At the time, ASPiRATION was the first-of-its-kind study in Australia to generate high quality, clinical and medical data to assess the impact and value of CGP, precision medicine and PHC in people with metastatic non-squamous non-small cell lung cancer (NSCLC).

"Broad genomic screening of a patient's tissue or blood samples may help clinicians to find rare and uncommon mutations that would not be economical to test for individually," said Ms Rossiter. "For people with rare and hard-to-treat cancers, this may lead to potential new treatment options that would have otherwise not been considered."

Led by Professor David Thomas, Chief Executive Of Officer of Omico, PrOSPECT aims to contribute to the increasing body of clinical evidence, which demonstrates participation in biomarker-driven clinical trials

improves cancer outcomes and represents an important treatment option for cancer patients, while also increasing the success rates of oncology clinical trials.1

"We know that every $1 AUD invested into local clinical trials returns $5 AUD to the Australian economy2,” said Mr Knight. "Roche is committed to delivering on this opportunity in a way that creates meaningful value for patients and healthcare systems."

"Roche stands ready to partner with all stakeholders, including governments, to shape the healthcare ecosystem of the future. By supporting Australian cancer patients to access the latest innovative treatment options through available local clinical trials, our ultimate goal is to improve their lives and the lives of their families and loved ones," said Mr Knight.


For all media enquiries, please contact Roche Products Pty Limited:

Amy O'Hara (0435 387 723) or Tania Jayesuria (0404 094 744)

Roche’s leadership in PHC

Roche is one of the world's leading innovative pharmaceutical and diagnostic companies in oncology healthcare. These combined strengths have made the company a leader in PHC – a strategy that aims to fit the right treatment to each patient in the best way possible. We contribute expertise and knowledge to the development and improvement of PHC to achieve better treatment outcomes. Through the use of comprehensive genomic profiling and processing of real-world data to support more systematic, equitable and sustainable access to oncology patients to targeted treatments; the ability to improve quality of life for patients with malignant diseases is within reach.

Our PHC efforts have already led to significant advances in healthcare and medicine, with measurable impact on patients, physicians and regulators. Roche is committed to delivering on this opportunity by drawing on a unique combination of strengths to drive this transformation: a leading portfolio of medicines, expertise in medicine, biology and data science, world-leading companies (Flatiron and Foundation Medicine), a network of partnerships and global reach.


About Roche

Roche is a global pioneer in pharmaceuticals and diagnostics focused on advancing science to improve people’s lives. The combined strengths of pharmaceuticals and diagnostics, as well as growing capabilities in the area of data-driven medical insights help Roche deliver truly personalised healthcare. Roche is working with partners across the healthcare sector to provide the best care for each person.

Roche is one of the world’s largest biotech companies, with truly differentiated medicines in oncology, immunology, infectious diseases, ophthalmology and diseases of the central nervous system. Roche is also a world leader of in-vitro diagnostics and tissue-based cancer diagnostics, and a frontrunner in diabetes management. In recent years, Roche has invested in genomic profiling and real-world data partnerships and has become an industry-leading partner for medical insights.

Founded in 1896, Roche has a robust 125-year legacy, focused on the search for better ways to prevent, diagnose and treat diseases and make a sustainable contribution to society. The company also aims to improve patient access to medical innovations by working with all relevant stakeholders. More than thirty medicines developed by Roche are included in the World Health Organization Model Lists of Essential Medicines, among them life-saving antibiotics, antimalarials and cancer medicines. Moreover, for the twelfth consecutive year, Roche has been recognised as one of the most sustainable companies in the Pharmaceuticals Industry by the Dow Jones Sustainability Indices (DJSI).

The Roche Group, headquartered in Basel, Switzerland, is active in over 100 countries and in 2021 employed more than 100,000 people worldwide. In 2021, Roche invested around CHF 13.7 billion in research and development worldwide, including over AUD 56 million in local pharmaceutical research in Australia. Genentech, in the United States, is a wholly-owned member of the Roche Group. Roche is the majority shareholder in Chugai Pharmaceutical, Japan.

Roche’s pharmaceutical division in Australia employs over 300 people who are dedicated to pioneering life-changing healthcare for every Australian via the clinical development, registration, sales, marketing and distribution of innovative pharmaceutical medicines. Australian patients have access to around 35 Roche medicines.


1. Parker JL, et al. Does biomarker use in oncology improve clinical trial failure risk? A large-scale analysis. Cancer Medicine 2021;10:1955–1963.

2. Australian Clinical Trials Alliance. Economic evaluation of investigator-initiated clinical trials conducted by networks. Sydney: ACSQHC; 2017.