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The BenchMark ULTRA PLUS instrument fully automates the processes of baking, deparaffinization, and staining for the qualitative or semi quantitative detection of analytes as an aid in diagnosis by pathologists. The system is intended for use in the anatomic pathology (AP) laboratory environment by trained laboratory personnel who are knowledgeable in histology processes and have basic computer operation skills.", "Language": "en", "Country": "XG", "Code": "Intended Use" }, { "Name": "Specification", "Value": "Instrument and consumables
Slide processing capacity30 independent slide drawers.
Slide tray positions1 to 30 positions, continuous access.
ThroughputApproximately 90 slides in 8 hours based on standard IHC samples.
Slide heater temperature37 °C to 90 °C +/- 2 °C
90 °C to 100 °C +2 °C /-3 °C
Reagent carousel35 reagent positions.
Slides25 × 75 mm (1 x 3 inches) or 26 × 76 mm positively-charged microscope slides.
Modularity1 to 4 BenchMark ULTRA PLUS instruments to one host computer is recommended for efficient processing, using VSS on the integrated touch screen monitor. Up to 8 instruments can be connected to the host computer if VSS is not used on the instrument touch screen monitor.
Bulk reagentsUp to 7 different bulk reagents in 3- to 6-liter continuous access on-board containers.
Internal system computerConnects to laboratory intranet or Roche Provided Network (switch box).
WasteTwo 20 L carboys and two 5 L carboys. Waste is segregated.

Dimensions and weight
SpecificationMetric measurement (Europe)Imperial measurement (US)
Height is less than or equal143 cm56 in.
Width is less than or equal115 cm45 in.
Depth is less than or equal89 cm35 in.
Instrument dry weight is less than or equal393 kg645 lb.
Size with rear covers removed (W x D x H) is less than or equal111 x 81.7 x 143 cm44 x 32.2 x 56 in.
", "Language": "en", "Country": "XG", "Code": "Specification" } ] } } ] }

BenchMark ULTRA PLUS system

Deliver diagnostic confidence with the BenchMark ULTRA PLUS system

IVD For in vitro diagnostic use.
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Deliver diagnostic confidence with BenchMark ULTRA PLUS system

Built upon the proven technology of the BenchMark ULTRA instrument, the BenchMark ULTRA PLUS system delivers an enhanced lab experience and an optimised workflow with flexible solutions. This easy-to-use solution helps histotechnologists and anatomic pathology laboratories manage activities efficiently and confidently, saving on personnel time and resource costs.


Key advantages of the BenchMark ULTRA PLUS system include:


  • New proprietary waste management solution with fewer user touchpoints
  • New integrated touchscreen for improved run management capabilities
  • New slide drawer design for improved reliability
  • The new VSS 14 intuitive software was developed from user feedback
  • Over 200 IVD ready-to-use assays for great laboratory workflow efficiency and consistency
Tissue image
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Flexible solutions
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Quality is at the core
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Optimised workflow
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Flexible solutions

New features based on user feedback:

  • New configuration has a decreased height compared to the BenchMark ULTRA instrument
  • New integrated touchscreen reduces bottlenecks by allowing many functions to be done at the instrument
  • VSS 14.x software allows for easier navigation of inventory management and ordering through a new filter as well as lot-to-lot validation on the same instrument
  • New proprietary waste management* solution degrades DAB (3,3'-diaminobenzidine) to less than 5 ppb meeting the most stringent municipality requirements for non-hazardous waste

*It is the responsibility of each customer to ensure compliance with all applicable laws and regulations related to the disposal of waste.

BenchMark Ultra Plus touchscreen close up
Quality is at the core

Proven BenchMark system technologies deliver the right stain at the right time:

  • Flexible, independent temperature control for individual slide staining optimisation
  • Proven staining technology of air vortex mixing with LCS create a reaction chamber allowing full slide coverage with 100ul of reagent
  • New slide drawer design mitigates fluid ingress and egress resulting in continuous and highly-reliable drawer performance
  • VSS 14.x software has new and expanded reporting capabilities including quality assurance/quality control (QA/QC)
BenchMark ULTRA PLUS glass stain
Optimised workflow

Improve usability while enabling time for more value-added activities through:

  • New light notifications communicate instrument status from across the lab
  • New retractable work surface gives technologists additional space to work while at the instrument
  • New bulk reagent color-coded clips make bulk reagent loading easier and helps minimise errors
  • New remote access allows you to view, manage, complete, and print system data remotely
  • New integrated communication allows streamlined data management and inventory tracking across all host computers
BenchMark ULTRA PLUS reagent colored clips

Would you like to know more about BenchMark ULTRA PLUS?


Submit your details in order to be contacted by a Roche representative with more details about BenchMark ULTRA PLUS and its availability in your region.

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General characteristics

  • Fully automated

    Baking, deparaffinisation, cell conditioning and staining, including IHC, ISH, SISH, immunofluorescence, multiparameter IHC staining (dual, triple), counterstain and titration

  • Slide position

    1–30 slides with independent processing/functionality and temperature control for each position

  • Reagent carousel

    35 reagent positions

  • Slides

    25 x 75 mm, 1 x 3 mm or 26 x 76 mm positively charged slides

  • Bulk solutions

    Up to 7 different bulk solutions can be changed without process interruption

    Only required bulk reagents needed on board

  • Waste

    Two 20 L carboys for processed aqueous waste

    Two 5 L bottles for separated LCS waste

    Virtually undetectable DAB in waste: <5 parts per billion

  • DI water supply

    NCCLS Type II water or equivalent (deionised water)

  • Temperature control

    Ambient to 100°C

  • Modularity

    1 to 4 BenchMark ULTRA PLUS instruments may be controlled from one BenchMark ULTRA PLUS computer system

  • Configuration

    Free standing

  • Certifications

    EN 61010-1, IEC/EN 61010-2-010, IEC/EN 61010-2-101, EN 61326-2-6

  • Catalog number

    N750-BMKU-FS 05342716001

Environmental requirements

  • BTU/Hour output

    400 BTU/Hr idle, 1000 BTU/Hr running

  • Room temperature

    68°F to 90°F (20°C to 32°C)

  • Humidity

    20% - 88%, non-condensing

Electrical specifications

  • Voltage


  • Current

    5-10 Amps

  • Frequency

    50/60 Hz

Physical characteristics

  • Size (W x D x H)

    44 X 35.25 X 59.15 in (111 X 89.5 X 150.2 cm)

  • Weight

    Instrument with reagents: 854.9 lbs (387.8 kg) full fluids, bulk, reservoirs and UV. Instrument dry: 606 lbs (275 kg)

  • Clearances

    Top 16.6 in (42.2 cm)
    Sides 4 in (10.2 cm)
    Rear 6 in (15.2 cm)

BENCHMARK is a trademark of Roche




Ordering Information

Technical Documents

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