Real-time PCR based donor screening test for chikungunya and dengue virus

cobas CV DV

Broad chikungunya and dengue coverage, ready to use

Duplex detection of emerging arboviruses

cobas® CHIKV/DENV is a duplex real-time PCR test for the detection of chikungunya virus RNA (CHIKV) and dengue virus RNA (DENV), for use on the cobas® 6800 and cobas® 8800 Systems.

Features and benefits

  • Provides coverage of all 3 major CHIKV genotypes: Asian, East/Central/South African and West African
  • Detects major serotypes of dengue virus (DENV serotypes 1-4)
  • Ready-to-use reagents—no thawing, pouring or mixing required
  • Stabilised real-time PCR reagents do not require calibration
  • Full-process internal control helps ensure result integrity
  • True external positive controls that have no effect on result calculation with cobas® CHIKV/DENV Control Kit

Reduce the risk of transfusion transmission

cobas® CHIKV/DENV was designed to run on the cobas® 6800 and 8800 Systems, simultaneously with other assays if desired. It can help meet changing demands for the detection of dengue virus, chikungunya virus, or both pathogens based on seasonal or regional testing needs.

Intended use

Intended use

cobas® CHIKV/DENV for use on the cobas® 6800/8800 Systems is a qualitative in vitro test for the direct detection of chikungunya virus (CHIKV) RNA and dengue virus (DENV) serotypes 1-4 RNA in human plasma.

The test is intended for use to screen donor samples for CHIKV RNA or DENV RNA alone or to simultaneously screen for both CHIKV and DENV RNA in plasma from individual human donors, including donors of whole blood, blood components, and other living donors. This test is also intended for use to screen organ and tissue donors when donor samples are obtained while the donor’s heart is still beating. Plasma from all donors may be screened as individual samples. For donations of whole blood and blood components, plasma samples may be tested individually or plasma may be tested in pools comprised of aliquots of individual samples.

This test is not intended for use of samples of cord blood.

This test is not intended for use as an aid in diagnosis for CHIKV or DENV.

Registration status