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Do not freeze.", "Language": "en", "Country": "XG", "Code": "Storage Conditions (Product)" }, { "Name": "Intended Use", "Value": "L’anticorps Myoglobin Rabbit Polyclonal Primary Antibody est destiné à l’usage en laboratoire pour la détection de la protéine myoglobine dans du tissu fixé au formaldéhyde, inclus dans la paraffine, coloré sur des instruments IHC/ISH VENTANA BenchMark. Ce produit doit être interprété par un pathologiste compétent en parallèle avec un examen histologique, les informations cliniques pertinentes et les contrôles appropriés. Cet anticorps est destiné à être utilisé aux fins de diagnostic in vitro (IVD).", "Language": "fr", "Country": "XG", "Code": "Intended Use" }, { "Name": "Content", "Value": "One dispenser of this antibody contains sufficient prediluted reagent for 50 tests.", "Language": "en", "Country": "XG", "Code": "Content" }, { "Name": "Background Information", "Value": "Immunostaining with anti-myoglobin provides a specific, sensitive, and practical procedure for the identification of tumors of muscle origin. Since myoglobin is found exclusively in skeletal and cardiac muscle and is not present in any other cells of the human body, it may be used to distinguish rhabdomyosarcoma from other soft tissue tumors.1-6

1. Mukai K, et al. Localization of myoglobin in normal and neoplastic human skeletal muscle cells using an immunoperoxidase method. Am J Surg Pathol. 1979; 3:373-6.
2. Corson JM, et al. Intracellular myoglobin--a specific marker for skeletal muscle differentiation in soft tissue sarcomas. An immunoperoxidase study. Am J Pathol. 1981; 103:384-9.
3. Brooks JJ. Immunohistochemistry of soft tissue tumors. Myoglobin as a tumor marker for rhabdomyosarcoma. Cancer. 1982; 50:1757-63.
4. Kahn HJ, et al. Immunohistochemical and electron microscopic assessment of childhood rhabdomyosarcoma. Increased frequency of diagnosis over routine histologic methods. Cancer. 1983; 51:1897-903.
5. Furlong MA, et al. Pleomorphic rhabdomyosarcoma in children: four cases in the pediatric age group. Ann Diagn Pathol. 2001; 5:199-206.
6. Furlong MA, et al. Pleomorphic rhabdomyosarcoma in adults: a clinicopathologic study of 38 cases with emphasis on morphologic variants and recent skeletal muscle-specific markers. Mod Pathol. 2001; 14:595-603.", "Language": "en", "Country": "XG", "Code": "Background Information" }, { "Name": "Principle", "Value": "Myoglobin Rabbit Polyclonal Antibody (this antibody) may be used as the primary antibody\nfor immunohistochemical staining of formalin-fixed, paraffin-embedded tissue sections. In\ngeneral, immunohistochemical staining allows the visualization of antigens via the sequential\napplication of a specific antibody (primary antibody) to the antigen, a secondary antibody\n(link antibody) to the primary antibody, an enzyme complex and a chromogenic substrate\nwith interposed washing steps. The enzymatic activation of the chromogen results in a visible\nreaction product at the antigen site. The specimen may then be counterstained and a coverslip\napplied. Results are interpreted using a light microscope and aid in the differential diagnosis\nof pathophysiological processes, which may or may not be associated with a particular\nantigen.\n
\n
\nThis antibody is optimally diluted to be compatible with VENTANA detection kits and\nBenchMark IHC/ISH instruments. Refer to the Tables in the Instructions for Use section for\nrecommended staining protocols. Each step in the staining protocol includes incubation for\na precise time at a specific temperature. At the end of each incubation step, the sections are\nrinsed by the BenchMark IHC/ISH instruments to stop the reaction and remove unbound\nmaterial that would hinder the desired reaction in subsequent steps. To minimize evaporation\nof the aqueous reagents from the specimen-containing slide, a coverslip solution is applied\nin the slide stainer. For more detailed information on instrument operation, refer to the\nappropriate BenchMark IHC/ISH instruments Operator’s Manual.", "Language": "en", "Country": "XG", "Code": "Principle" }, { "Name": "Product Purpose", "Value": "L’anticorps Myoglobin Rabbit Polyclonal Primary Antibody est destiné à l’usage en laboratoire pour la détection de la protéine myoglobine dans du tissu fixé au formaldéhyde, inclus dans la paraffine, coloré sur des instruments IHC/ISH VENTANA BenchMark. Ce produit doit être interprété par un pathologiste compétent en parallèle avec un examen histologique, les informations cliniques pertinentes et les contrôles appropriés. Cet anticorps est destiné à être utilisé aux fins de diagnostic in vitro (IVD).", "Language": "fr", "Country": "XG", "Code": "Product Purpose" } ] } } ] }

Myoglobin Rabbit Polyclonal Antibody

IVD For in vitro diagnostic use.
Myoglobin Rabbit Polyclonal Antibody

Description

Detailed Specifications

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