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"Classification": [ { "IdentifierofStructureSystem": "Product_Grouping", "NameofStructureSystem": "Product Grouping", "StructureNodeID": "03-0703", "StructureGroupPath": "Molecular->MagNA Pure 96 Accessories and Consumables", "StructureGroupName": "MagNA Pure 96 Accessories and Consumables" }, { "IdentifierofStructureSystem": "OWP_Family", "NameofStructureSystem": "Product Families", "StructureNodeID": "260", "StructureGroupPath": "MagNA Pure", "StructureGroupName": "MagNA Pure" }, { "IdentifierofStructureSystem": "OWP_Product_Types", "NameofStructureSystem": "Product Types", "StructureNodeID": "50-000-00", "StructureGroupPath": "Consumables", "StructureGroupName": "Consumables" }, { "IdentifierofStructureSystem": "Lab_Type", "NameofStructureSystem": "Lab Types", "StructureNodeID": "010-00", "StructureGroupPath": "Molecular Lab", "StructureGroupName": "Molecular Lab" }, { "IdentifierofStructureSystem": "Product_Solutions", "NameofStructureSystem": "Product Solutions", 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"99-00-00", "StructureGroupPath": "NOT APPLICABLE", "StructureGroupName": "NOT APPLICABLE" }, { "IdentifierofStructureSystem": "Health_Topics", "NameofStructureSystem": "Health Topics", "StructureNodeID": "99-00-00", "StructureGroupPath": "NOT APPLICABLE", "StructureGroupName": "NOT APPLICABLE" } ] }, { "ProductID": "3.8.11.3.4.1", "BrandName": "Tip CORE TIPS with Filter, 50uL", "ProductNameAddition": "", "ReferenceType": "Consumable", "Classification": [ { "IdentifierofStructureSystem": "Product_Grouping", "NameofStructureSystem": "Product Grouping", "StructureNodeID": "06-0006", "StructureGroupPath": "LifeScience->FLOW System Accessories & Disposables", "StructureGroupName": "FLOW System Accessories & Disposables" }, { "IdentifierofStructureSystem": "OWP_Product_Types", "NameofStructureSystem": "Product Types", "StructureNodeID": "50-000-00", "StructureGroupPath": "Consumables", "StructureGroupName": "Consumables" }, { "IdentifierofStructureSystem": "Lab_Type", 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"NameofStructureSystem": "Disease Areas", "StructureNodeID": "99-00-00", "StructureGroupPath": "NOT APPLICABLE", "StructureGroupName": "NOT APPLICABLE" }, { "IdentifierofStructureSystem": "Pathogens", "NameofStructureSystem": "Pathogens", "StructureNodeID": "99-00-00", "StructureGroupPath": "NOT APPLICABLE", "StructureGroupName": "NOT APPLICABLE" }, { "IdentifierofStructureSystem": "OWP_Family", "NameofStructureSystem": "Product Families", "StructureNodeID": "999", "StructureGroupPath": "NOT APPLICABLE", "StructureGroupName": "NOT APPLICABLE" }, { "IdentifierofStructureSystem": "Health_Topics", "NameofStructureSystem": "Health Topics", "StructureNodeID": "99-00-00", "StructureGroupPath": "NOT APPLICABLE", "StructureGroupName": "NOT APPLICABLE" } ] } ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "fr", "Value": "Le MagNA Pure 24 System est un système de purification des acides nucléiques automatisé qui comprend le MagNA Pure 24 Instrument, le logiciel, les consommables et les réactifs. Le MagNA Pure 24 System doit être utilisé par des professionnels pour la purification des acides nucléiques à partir d’échantillons biologiques dans le cadre du diagnostic in vitro.", "Country": "XG", "Code": "Intended Use", "Name": "Intended Use" }, { "Language": "en", "Value": "About run types and workflows

The MagNA Pure 24 System offers 4 run types:

Purification (rack) run
In a purification (rack) run, the instrument pipettes sample material from sample tubes, processes it, and transfers the eluates to the output consumables in the cooling station.
The purification (rack) run is the fully automated combination of a sample transfer run and a purification (cartridge) run.

Purification (cartridge) run
In a purification (cartridge) run, the processing cartridges are pre-filled with sample material, either in a previous sample transfer run, or by manual pipetting. The instrument processes the sample material, and transfers the eluates to the output consumables in the cooling station.
In the case of a previous sample transfer run, open the corresponding order to load sample details.

Post elution run
In a post elution run, the instrument pipettes eluates into 8-tube strips (either empty or containing manually prepipetted PCR master mix reagent). From each eluate, the instrument pipettes up to 2 eluate aliquots. Additionally, the instrument pipettes controls. Sample information from a previous purification run is loaded when reading the barcodes of the eluate output consumables.
A post elution run uses the cooling station only and requires a dedicated post elution adapter.

Sample transfer run
In a sample transfer run, the instrument pipettes sample material from sample tubes into processing cartridges.
You can then use the sample-filled processing cartridges in a purification (cartridge) run.

The run types differ in input and output and use different instrument stations.(see Fig. 2).
 
", "Country": "XG", "Code": "Principle", "Name": "Principle" }, { "Language": "en", "Value": "For safety related information refer to the MagNA Pure 24 Safety Manual.

Chemical reaction producing toxic gas
Mixing bleach or DNA AWAY™ Surface Decontaminant with reagents can result in a chemical reaction that produces a highly toxic gas.
-> Do not allow reagents containing guanidine thiocyanate to contact sodium hypochlorite (bleach) solution or acids.
See also the reference from the FDA: Transport Media Safety Risk - Use Compatible Transport Media with SARS-CoV-2 Tests that Use Bleach - Letter to Clinical Laboratory Staff and Health Care Providers.", "Country": "XG", "Code": "Safety Information", "Name": "Safety Information" }, { "Language": "en", "Value": "The MagNA Pure 24 System is a fully automated clinical sample extractor. It extracts nucleic acids from various sample types, sample tubes, and volume inputs for multiple downstream applications.
The main features of the system are:

  • Scalable purification of 1 to 24 samples
  • Primary/secondary tube handling
  • Inventory and sample management via barcodes
  • Efficient order management via host
", "Country": "XG", "Code": "Product Description", "Name": "Product Description" }, { "Language": "en", "Value": "1. MagNA Pure 24 Instrument
2. Built-in control unit with preinstalled MagNA Pure 24 operating software and purification protocols
3. MagNA Pure 24 Accessories
4. Digital User Assistance", "Country": "XG", "Code": "Content", "Name": "Content" } ] } } ] }

Système MagNA Pure 24

Démarrez ici. Allez où vous voulez.

Image produit du système MagNA Pure 24

Entrez dans un nouveau monde de productivité.

 

Commencez ici. De nombreuses possibilités s'offrent à vous.

 

Depuis des années, les laboratoires de biologie moléculaire font confiance à la famille de produits MagNA Pure. Ces derniers leur permettent de réduire les erreurs de manipulation grâce à une préparation fiable et simplifiée des échantillons. Le système MagNA Pure 24 est un extracteur d'échantillons cliniques entièrement automatisé. Il exploite tout l'héritage de la famille de produits MagNA Pure et a été conçu pour minimiser le temps de manipulation et la variabilité de la purification.

Purification sans effort, fiabilité grâce à l’automatisation1

  • Une performance prouvée pour des rendements reproductibles et constants
  • Extraction de 24 échantillons au maximum avec manipulation des échantillons primaires en un peu plus d’une heure
  • Une seule trousse de réactifs universelle pour 8 types d’échantillons humains et des quantités d’échantillons comprises entre 200 µl et 4 ml
  • Traçabilité complète grâce à la vérification de la présence de l’ensemble des composants de purification et des échantillons grâce aux codes-barres
  • Minimisation du temps de manipulation
  • La lampe UV intégrée et la technologie CO-RE contribuent à prévenir la contamination

 

Les trousses de réactifs pré-remplis et prêts à l'emploi sont dotées d'un code-barre1

 

La trousse universelle du système MagNA Pure 24 Total Nucleic Acid Kit élimine toute complexité inutile et permet l’extraction efficace des acides nucléiques issus de 8 types d’échantillons humains prévalidés grâce à une seule trousse de réactifs universelle. Les cassettes de réactifs peuvent être scellées pour une réutilisation ultérieure, et le système identifie et vérifie la consommation de réactifs grâce au lecteur de codes-barres intégré.

 

Davantage de flexibilité pour votre laboratoire1

 

Le système MagNA Pure 24 permet l’extraction des acides nucléiques issus de 8 types d’échantillons humains avec une seule trousse de réactifs universelle. Faites confiance à ce concept de réactifs simplifié et sélectionnez l’un des protocoles pré-optimisés et préprogrammés pour les extractions à partir de lots composés de différents types d’échantillons et tubes primaires avec un seul et même protocole.

L’efficacité en toute simplicité1

Le système MagNA Pure 24 n'est pas seulement automatisé. Il offre une autonomie longue durée avec une surveillance simple grâce aux codes-barres et une intervention minimale de l’utilisateur, ce qui réduit le risque d’erreurs et permet de gagner un temps précieux.

 

  • Configuration facile de l’extraction
  • Interface utilisateur intuitive et guidée sur l'écran tactile intégré
  • Exécution du protocole court pour un maximum de 8 échantillons en 30 minutes ou moins
  • Vérification du chargement en moins de 30 secondes
  • Démarrage rapide du système (<5 minutes)
  • Gestion transparente des données via le système d’information du laboratoire (LIS)
  • Extraction entièrement automatisée des échantillons FFPE avec le déparaffinage intégré et une étape de lyse

 

Un système fiable1

 

Pour les tests de biologie moléculaire, la confiance dans l’éluat est essentielle. Le système MagNA Pure 24 est un dispositif médical de diagnostic in vitro (IVD) doté d’une fonction de suivi permettant de garantir une qualité maximale des éluats et de réduire les erreurs dues à l’utilisateur.

 

  • Fonctions pour le contrôle des contaminations et de la sécurité
  • Codes-barres pour le suivi de l’identifiant des échantillons et de la consommation des réactifs
  • Bloc réfrigérant pour la conservation des éluats
  • Logiciel traçable avec piste de gestion d'audit
  • Archivage des données générées grâce au logiciel MagNA Pure 24 version 1.1
  • Visualisez les données sur votre PC à l’aide de l’outil visualiseur de données.

Référence :

  1. Guide utilisateur MagNA Pure 24, v 2.0, 10/2020

Le MagNA Pure 24 System est un système de purification des acides nucléiques automatisé qui comprend le MagNA Pure 24 Instrument, le logiciel, les consommables et les réactifs. Le MagNA Pure 24 System doit être utilisé par des professionnels pour la purification des acides nucléiques à partir d’échantillons biologiques dans le cadre du diagnostic in vitro.
Dispositif médical de diagnostic in vitro. Classe A
Mandataire : Roche Diagnostics GmbH (Allemagne) – Distributeur : Roche Diagnostics France
Lire attentivement les instructions figurant dans le manuel d'utilisation

Mis à jour : 09/2022

Aperçu

Commander

Documents techniques

Protocoles du système MagNA Pure 24

Le nouveau pack de protocoles 3.0 du système MagNA Pure 24 est téléchargeable dans le tableau ci-dessous :

 

Les protocoles suivants ont été mis à jour :

  • hgDNA 200 Version 3.1
  • Fast hgDNA 200 Version 3.1
  • hgDNA ds 200 Version 3.1
  • Pathogen 200 Version 3.1
  • Pathogen 1000 Version 3.1
  • External Lysis Pathogen 500 Version 2.0
  • Sample Transfer Version 3.1

 

Afin de pouvoir accéder aux nouveaux protocoles listés ci-dessus, suivre les étapes de paramétrage suivantes :

Etape 1 : Sélectionner la cassette de réactifs "Total NA Isolation Kit 1.1"

Etape 2 : Sélectionner le type d'échantillon

Etape 3 : Sélectionner le volume d'échantillon

Etape 4 : Sélectionner le protocole

Global run settings
Protocoles du système MagNA Pure 24
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Target  Protocol name Input sample type and sample volumes
The latest version of MagNA Pure 24 protocols are available to download from the table below (not available in US)
 Elution volume  Run time♰ (h:mm)
 Whole blood  Plasma  Serum Nasal swabs*  BAL**
 Urine  Stool  Cultured cells Fresh-frozen tissue FFPET***
Bacterial, fungal and viral NA Pathogen 200  

Protocol optimized for speed

200 μL   50 or 100 μL 1:22
Fast Pathogen 200  

8 sample protocol optimized for speed, yield and purity

  0:35
Pathogen 1000

Protocol optimized for yield and purity

500 or 1000 μl   1:40
External Lysis Pathogen 200
External Lysis Pathogen 500  

Protocols optimized with external lysis buffer

450 μl lysate from 200 μl sample
1450 μl lysate from 500 μl sample
  1:30
1:40
Genomic DNA hgDNA 200  

Protocol optimized for human genomic NA

200 μl (≤ 2x106 cells)   Up to 5x105 Up to 5 mg   1:15
Fast hgDNA 200  

8 sample protocol optimized for speed

  0:25
hgDNA ds 200  

Protocol optimized for NGS

1:15
hgDNA 1000  

Protocol optimized for yield and purity

500 μl (≤ 5x106 cells)
1000 μl (≤ 1x107 cells)
100 or 200 μl 2:25
Up to 1x106
DNA FFPET 1000  

Deparaffinization and lysis on board

  Up to 6 x 5 μm sections (up to 6 mm3) 50 or 100 μl 5:30
Cell-free NA cfNA ss 2000
cfNA ss 4000  

Protocol optimized for single-stranded DNA

  2000 μL   50 or 100 μL 2:05
4000 μL 3:00
cfNA ds 2000
cfNA ds 4000  

Protocol optimized for double-stranded DNA

  2000 μL   100, 150 or 200 μL 2:30
4000 μL 3:30
cfNA ds 4000 hp  

Protocol optimized for double-stranded DNA and NGS

  4000 μL   60 or 150 μL 4:40
Post elution Sample Transfer   to the processing cartridge 200 μL
500 μL
1000 μL
  0.08
PCR Setup   for 2-25 μL per eluate for PCR Sstup in Frame-Strip with flat caps-Low Profile or LightCycler® 8-tube strips   0.05
Archiving   for 2-25 μL per eluate for PCR Sstup in FrameStrip low Profile strips or LightCycler® 8-tube strips 0.05
New Protocol
*Nasopharyngeal/nasal swabs
**BAL - Bronchoalveolar lavage
***FFPET - formalin-fixed paraffin-embedded tissue
♰These times are approximate and should only be used as a guidance.
Retour     En avant
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