Elecsys® Anti-HAV II is an immunoassay for the in vitro qualitative detection of total (IgM and IgG) antibodies to HAV in human serum and plasma. It is used as an aid to detect a past or existing HAV infection or to determine the presence of antibody response to HAV in vaccine recipients.11
Hepatitis A
Hepatitis A is an acute, inflammatory liver disease caused by infection with the hepatitis A virus (HAV). HAV is a non-enveloped RNA virus in the family of picornaviruses. Of the 7 known genotypes, 4 can infect humans. Only one serotype of HAV has been documented.1-5
Hepatitis A occurs sporadically and in epidemics worldwide, with around 1.4 million new HAV infections reported each year.3,4 HAV is transmitted fecal-orally either by person-to-person contact or ingestion of contaminated food or water in regions of low hygienic standards. Cooked foods can transmit HAV if the temperature during food preparation is inadequate to inactivate the virus or if food is contaminated through infected food handlers.1,4-6