HPV mRNA Probes

Raw material for use in laboratory developed tests (LDTs)/ Analyte Specific Reagent*

HPV mRNA Probes
HPV mRNA ISH probes
  • HPV E6 and E7 are biologically relevant markers.
  • Raw material for laboratory developed tests (LDTs)/Analyte Specific Reagent.*
  • The HPV mRNA probes are DNP hapten labeled probes designed to bind to their respective HPV E6/E7 mRNA transcripts.
  • Five HPV mRNA probes are available:  HPV 6, HPV 11, HPV 16, HPV 18 and HPV 33.
Cell Cycle Control Mechanisms of the HPV Virus
HPV E6 E7 Oncoprotein expression

Figure 1. Two of the early HPV genes encode for the oncoproteins E6 and E7. mRNA transcription in cells indicates active viral processes. Overexpression of E6 and E7 mRNA precedes transformation of cells. In persistent high risk HPV infections, E6 and E7 oncoproteins disrupt the p53 and retinoblastoma protein (pRb) cell cycle control mechanisms respectively.


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Product Name

Catalog Number Ordering Code

HPV 6 mRNA Probe

760-1239 07658877001

HPV 11 mRNA Probe

760-1240 07658885001

HPV 16 mRNA Probe

760-1236 07658834001

HPV 18 mRNA Probe

760-1237 07658842001

HPV 33 mRNA Probe

760-1238 07658869001

* Analytical and performance characteristics are not established.