Article

Advancing CVD Management with Digital Triage Tools in the emergency room

Digital triage support tools for cardiovascular disease in the emergency room
Cardiovascular disease and the use of technology in the Emergency Room

Cardiovascular disease (CVD) encompasses a range of conditions, including coronary artery disease, heart failure, arrhythmias, and stroke. According to the World Health Organization (WHO), CVD accounts for approximately 17.9 million deaths annually, representing 31% of all global deaths.1 The broad presentation of CVD often requires immediate and precise intervention to improve patient outcomes. About 20% of emergency room visits are preventable, with half being for cardiovascular conditions.2 The complexity of diagnosing and managing CVD, particularly in the emergency room, necessitates advanced digital triage tools to support clinical decision making and reduce emergency room visits.

 

The role of clinical decision support tools (CDSTs)

 

Clinical decision support tools (CDSTs) are computer-based systems designed to assist healthcare professionals during emergency room triage and follow-up. They integrate patient data, clinical guidelines, and predictive algorithms to provide tailored and specific treatment recommendations. These tools can enhance diagnostic accuracy, streamline workflows, support timely interventions, and improve adherence to guidelines, ultimately leading to better patient outcomes.3,4 However, challenges to their implementation include poor familiarisation of physicians with technology, integration difficulties with electronic health records, and bandwidth issues within the digital health infrastructure.

One of the primary applications of CDSTs in CVD management is during chest pain triage to enhance diagnostic accuracy. For example, CDSTs can analyse high-sensitivity troponin (hs-troponin) levels along with other clinical parameters to stratify a patient’s risk of CVD and guide further testing or treatment.5,6

 

The current triage of chest pain patients is done using an algorithm that is part of the ESC [European Society of Cardiology] recommendations, so patients have to have a pretest probability for the disease or for acute coronary syndrome

 Dr. Giannitsis

 

The implementation of electronic health records integrated with CDSTs can also improve the efficiency of patient care by reducing the time spent on documentation.7

 

Expert opinions on CDSTs

 

Professor Christopher Baugh and Professor Evangelos Giannitsis highlight the significant role of digital decision support tools in the emergency room. They discuss that crowding, staffing shortages, and high patient throughput are the biggest challenges in the emergency room. CDSTs can aid in the accurate classification and triage of patients, potentially addressing these challenges.

 

Real-world examples and benefits

 

Several digital technologies have been developed for the management of CVD within the emergency room. Notable examples include the HEART score and the Global Registry of Acute Coronary Events (GRACE) score, both of which aid in risk stratification and have been shown to improve the efficiency of care.8-11

The HEART score is a widely used interactive tool for risk stratification in patients with chest pain. It incorporates five elements: patient history, ECG, age, risk factors and troponin levels and categorises patients into low, intermediate, and high-risk groups, guiding further diagnostic and therapeutic decisions.8 Studies show that its use can reduce unnecessary admissions and improve the efficiency of care in the emergency room.9

The GRACE score is used to predict the risk of death and AMI in patients with acute coronary syndrome (ACS) by integrating clinical variables such as age, heart rate, systolic blood pressure, and creatinine levels.10 The use of the GRACE score in the emergency room has been associated with an improved risk prediction of mortality in patients with ACS and can help identify high risk patients who may benefit from more aggressive treatment and close monitoring.10,11

 

Electronic solutions can overcome some limitations, for example, improve guideline adherence and improve quality of care for patients. They even can reduce the length of hospital stay and therefore increase patient satisfaction and reduce costs for staff, patient treatment and monitoring. 

Dr. Baugh

 

Recent advancements in artificial intelligence (AI) have also led to machine learning algorithms that provide high accuracy in predicting patient outcomes and guiding treatment plans. Machine learning algorithms can also be used to predict the risk of adverse events, such as heart failure exacerbations, allowing for early intervention and improved patient outcomes.12 A recent study demonstrated serial ECGs from an individual had greater ability to predict new‐onset atrial fibrillation than an AI machine learning model based on a single ECG.13

Clinical decision support tools offer numerous benefits, including improved diagnostic accuracy, enhanced patient outcomes, and reduced healthcare costs. By integrating multiple data sources and applying evidence-based algorithms quickly, CDSTs reduce the likelihood of diagnostic errors and ensure that patients receive appropriate care promptly.3 Studies demonstrate that CDSTs in managing acute coronary syndrome (ACS) can reduce mortality and morbidity rates and support personalised care by tailoring recommendations to individual patient characteristics.12,14

 

Challenges and limitations

 

While CDSTs provide broad benefits, challenges remain, including data quality and completeness, user acceptance, and ethical and legal considerations. Accurate data input and seamless integration with existing electronic health record systems are crucial for successful implementation. Overcoming resistance to change and ensuring healthcare professionals are adequately trained are essential for the adoption of CDSTs. Professor Giannitsis suggests there is poor familiarisation with digital devices in a very heterogeneous healthcare landscape. Additionally, addressing bandwidth issues within the digital health infrastructure is necessary for the widespread use of these tools.

 

Future prospects

 

"There is a lot of excitement over what AI could bring to complement the clinician, to make him or her more efficient and safer in their practice of emergency medicine and to take them away from the computer and to the bedside where they want to be spending their time,” said Dr. Baugh. Advancements in technology and data science offer new opportunities for their use in emergency rooms and broader clinical practice. The integration of CDSTs with wearable devices and remote monitoring systems can provide continuous data on patients' cardiovascular health, enabling early detection and proactive management.15 Furthermore, the use of CDSTs in clinical research can enhance patient recruitment, retention, and the development of new clinical guidelines.

 

Conclusion

 

CDSTs have the potential to revolutionise the management of CVD in the emergency room by improving diagnostic accuracy, streamlining workflows, and supporting timely interventions. Addressing challenges related to data quality, user acceptance, and ethical considerations is essential for their successful implementation. Ongoing advancements in technology hold promise for further enhancing personalised medicine and clinical research. By embracing CDSTs and integrating them into routine emergency room practices, healthcare professionals can significantly improve patient outcomes and quality of life for those with CVD.

 

We have to improve healthcare delivery for the sake of the patient and every effort that we make is beneficial for them. I believe that implementation of clinical decision tools using algorithms that are based on knowledge and on guidelines will be very helpful in the future.

Dr. Giannitsis

Video transcript

CB: I would say in my role at Brigham and Women's Hospital working in the emergency department the three biggest challenges are crowding, staffing and patient throughput. I mention crowding. That's really inpatient crowding, so their inpatient services are full. When those patients are waiting for beds upstairs, they accumulate in the emergency department. And that kind of shunts beds away from newly arriving patients to the emergency department. As a result, we're seeing a large portion of our patients in hallways and there's a big risk in waiting room census being very high. The next is staffing. We're seeing a huge staffing crisis right now, affecting in particular nurses, but also, medical assistance, transporters, techs of all kinds. And as a result, we have fewer staff to take care of more patients and that leads to staff burnout, which then exacerbates the staffing problem. And the last is throughput. As you can imagine, in a setting with fewer staff and fewer resources, the importance of getting patients safely through their visit in the emergency department, with all the treatments and diagnostics we do, is even more crucial today than ever before. So we're really struggling with finding the right timing and throughput of testing, in order to get people through their journey as safely and efficiently as possible. 

EG: As the head of the Chest Pain Unit, I see a crowding of patients. There is a shortage of bed capacities in the hospital and therefore we need to triage patients into safe discharge and select patients who are ideal candidates for admission. The major challenges in digital healthcare is the poor familiarization of physicians with this kind of digital devices and the very heterogeneous landscape. For example availability of electronic health records in hospitals even in Germany. 

CB: The two main challenges for digital health right now are translating the protocols that we have written down really through traditional methods. These could be kind of written on whiteboards on laminated posters around the department getting them translated into our electronic medical record environment. And so making that switch from essentially paper to electronic has been very challenging because that integration is harder than you might assume because the clinical experience of interacting with these protocols is somewhat challenging to get right and as a result exposed to a lot of digital tools that are well intentioned but really not working very well. The other main challenge that we have is a lack of bandwidth among the digital health infrastructure because there are so many competing demands on their time. And as a result, there's usually big lags between when we identify something that needs to be improved and when it's actually implemented. For example we have lots of quality and safety problems that need to be fixed with a digital tool solution. We have times when the digital tool goes down and needs to be put back up from an IS downtime or just a server going down or something like that. So the idea of actually thinking ahead for improvement to bring something new into that environment you're competing with these other things on the list and as a result it's very difficult to get things done. 

EG: Electronic solutions can overcome some limitations. They can for example improve guideline assurance and improve the quality of care for patients. And they even can reduce the length of hospital stay therefore increase patient satisfaction and reduce also costs for staff for treating patients and monitoring. The requirements for implementation of new digital tools to impact practice are really based on three pillars. I would say first, it needs to be clinically correct. The underlying recommendation needs to actually resonate with the clinician and feel valuable to the clinician. Secondly it needs to be well integrated into the medical record. It has to be able to speak with a record that the user can't go out of the record in order to access the tool. And then third it needs to be a business case for the leadership to embrace bringing that tool into a particular environment. And so if any one of those three pillars is missing, then the tool is going to have a really uphill battle in order to get adoption. And so you really need to consider each of those three when you're looking to integrate. Digital tools can impact patient care in the emergency department really by giving a better classification of patients by shrinking that observation or gray zone and more accurately classifying patients who are either ruling in or need further hospital based diagnostics or ruling out and being able to be safely discharged home. I think right now there is some confusion around that kind of observation or gray zone. And so if we can shrink that as much as possible through these tools, I think that'll be a great benefit. I think also giving a bit of confidence to the physicians that they can stop testing the low risk patients and safely get them home without causing harm to those patients will help reduce unnecessary testing and hospital resource use. The current triage of chest pain patients is done using an algorithm that is part of the ESC recommendations. So patients have to have a pre-test probability for the disease, for acute coronary syndrome. Then if this is true then they will have an EKG. And if the EKG is normal, they will have biomarker testing with high sensitivity troponins. And the triage algorithm currently is proposing a baseline value and subsequent testing after 60 minutes or after two hours the so called ESC 0/1h, 0/2h algorithm And with this, the patients are triaged into a rule-out zone, a rule-in zone, and into an observational zone if neither category fits. Digital tools could improve this triage that has some limitations. The most important limitation of the current triage is that the time between blood sampling is not, correctly considered. So it's used as a default, but not actually the elapsed time between blood samples. And second, the numbers of required blood samples are often not fulfilled. So they are protocol violations in the number of blood tests. Sometimes the second blood draw is omitted, and sometimes there are excessive blood draws beyond the diagnostic set. The main trends that we're seeing right now in digital healthcare are risk prediction and machine learning or artificial intelligence being integrated into digital tools. Right now there's a lot of effort put into not just calculate, simple risk scores but actually use machine learning to give a percentage, perhaps of risk or need for hospitalization. And having that information earlier in the emergency department stay might help with kind of anticipating that disposition later in their stay, as well as trying to make a safe disposition of keeping a patient you might have otherwise discharged home. And then what we're seeing more and more right now is a lot of excitement over what AI could bring as a complement to the clinician in order to make him or her more efficient and safer in their practice of emergency medicine, to take them away from being at the computer so much and actually put them more at the bedside where they want to be spending their time. I think that we have to improve health care delivery for the sake of the patient. And every effort that we are doing is beneficial for a patient. And I believe that implementation of clinical decision tools using algorithms that are based on knowledge on guidelines or even, importing artificial intelligence into these systems will be very helpful in the future.

Key facts

  • Clinical decision support tools (CDSTs) can significantly improve diagnostic accuracy and streamline workflows in the emergency department. By integrating these tools healthcare professionals are assisted in making timely and precise decisions, leading to better patient outcomes, reduced diagnostic errors and more efficient use of healthcare resources.3,4
  • CDSTs can support the shift towards personalised medicine by tailoring recommendations to individual patient characteristics. Using high-quality robust data, machine learning algorithms and real-time data analytics, digital triage tools enable the early identification of either high- or low-risk patients and the delivery of personalised treatment plans. This also reduces healthcare costs by preventing potential complications and unnecessary clinical interventions.
  • Future advancements, including the integration with wearable devices, genomic data, and telemedicine, hold promise for further enhancing the capabilities and impact of CDSTs in cardiovascular disease (CVD) patient management.

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References

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