CoaguChek® XS Plus system

Coagulation monitoring for healthcare professionals

Product image for CoaguChek ® XS Plus system

Coagulation monitoring for healthcare professionals


CoaguChek® XS Plus provides accuracy, ease of use plus data management for recording patient IDs.

Test your patients’ PT/INR right in your practice instead of waiting for lab results. All three CoaguChek XS devices use the same testing technology. So the CoaguChek XS Plus and Pro produce results equivalent to those obtained with reference laboratory methods and also compare closely to the patient’s device, the CoaguChek XS.

CoaguChek XS plus system

PT/INR Monitoring tailored to a healthcare professional’s needs


CoaguChek XS Plus system has the CLIA-waived status. The point-of-care anticoagulation monitor offers connectivity and data management tools to help healthcare professionals manage PT/INR (blood clotting time) testing. The waiver means that the monitoring technology may now be used in a broader range of clinical settings, such as labs that do not meet the requirements to perform moderate- or high-complexity testing as defined by the CLIA of 1988.1

CoaguChek XS Plus

The CoaguChek® XS Plus meter features

Accurate and flexible technology–a smart way to test


  • Accurate, precise results in about one minute2
  • The only system to perform onboard quality control and patient tests in a single test chamber
  • Results unaffected by heparin at therapeutic levels3
  • INR corrected for hematocrit within specified range


Streamlined data management


  • Stores 2000 patient and 500 QC test results
  • Operator and QC lockout to ensure your policies are followed
  • Calibration via code chip
  • Stores lot data for up to 60 codes

System components

  • 1 CoaguChek XS Plus instrument
  • 1 Handheld power supply unit
  • 1 printed manual in English
  • 1 CD-ROM with other languages: German, French, Italian,
  • English, Spanish, Portuguese, Danish, Norwegian, Swedish, Finnish and Dutch


Optional accessories


  • Handheld base unit kit: docking station (to reload the battery pack and transfer data to a computer)
  • Handheld battery pack: option instead of standard batteries or power supply (to gain flexibility)


Additional required components


CoaguChek XS PT Test strips (in a vial)

  • Box with 2 vials of 24 strips with a code chip
  • Box with 1 vial of 24 strips with a code chip

Optional international 1 level CoaguChek XS PT-control kit including:

  • 4 vials with a concentration of ~ 2.0 INR
  • 4 diluent-filled droppers
  • 1 code chip
  • Package insert
CoaguChek Pro II



  1. Roche Diagnostics, Method Sheet CoaguChek XS PT Test, 2017, US version.
  2. Roche Diagnostics, User Manual CoaguChek XS Plus System, 2009.
  3. Roche Diagnostics, Method Sheet CoaguChek XS PT Test, 2018, EU version.
System specifications

System specifications

Detection system

Amperometric (electrochemical) determination of the PT/INR after activation of the coagulation with human recombinant thromboplastin


User interface

Full graphical (TFT)


Support and safety functions

QC lockout, Patient & User ID, protection with administrator ID


Sample application

Outside the meter, with top-and 2 sides (left or right)-dosing options

Operating temperature

+15° C to +32 °C (59 °F to 90 °F)


Operating humidity and altitude

10 - 85% - 4300 m



  • First option: Operate the monitor on a level surface, free of vibrations
  • Second option: hold the monitor in your hand, so that it is roughly horizontal


Measuring range

INR: 0.8 - 8.0; %Q: 120 - 5; SEC: 9.6 - 96



  • 2000 patient and 500 QC results with date and time.
  • 60 code chip records.
  • Operator lists with up to 5000 Operator IDs with corresponding 2nd ID.
  • Patient lists with up to 4000 Patient IDs with corresponding 2nd and 3rd IDs.



Infrared interface


Power options

  • Power supply adaptor: input: 100 - 240 V / 50 - 60Hz / 400 mA; output: 7.5 V DC/ 1.7 A
  • 4 x 1.5 V AA batteries (alkali - manganese)
  • Rechargeable battery pack (optional)


Number of tests per set of batteries

Approx. 80 tests (approx. 60 tests per charging cycle if the rechargeable battery pack is used)



185 x 97 x 43 mm



311 g (without batteries)

Sample type

Fresh capillary whole blood or non-anticoagulated venous whole blood


Sample size

≥ 8 μl



Refer to the test strip package insert


Approx. 1.0


Sensitivity to heparin

Not at therapeutic levels, up to 0.8 I.U/ml for UFH and to 2 anti - Xa.U/ml for LMWH


Quality control

On each strip, through the same channel as the blood passes



21 months from production (+ 2° C to + 30° C)