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LightCycler® PRO system

Light the way from research to clinical diagnostics
The LightCycler® PRO system combines the functionalities of instrumentation, consumables, reagents, and data management to support a semi-automated workflow for polymerase chain reaction-based nucleic acid testing.1
Leveraging the robustness and proven technology of the LightCycler® 480,* the LightCycler PRO integrates innovative technology and Roche manufacturing to deliver accurate real-time PCR results and an improved user experience for your lab.
Increase your lab’s testing capabilities
TIB Molbiol provides a comprehensive assay menu for both research and clinical diagnostic uses.** This includes the LightMix® Modular Assay Kits, which are meticulously tailored for optimal performance on the LightCycler® PRO system, ensuring user-friendly convenience without compromising result quality, reliability, or reproducibility.

Delivers multiplex precise data analysis
The new LightCycler® PRO software improves functionality, performance, and precise data analysis.2
A new adaptive color compensation function across the 7 channels to minimize color crosstalk. This methodology is optimized for use with LightMix® modular assays.
An updated fit points algorithm that automatically determines the Cq value from the PCR run data for confidence in results calling

TIB Molbiol LightMix® Modular Gastro Bacteria 7-target multiplexed assay. Optimized to detect 7 different targets from a single well.

LightCycler® PRO System, dilution series 10^1 to 10^8 copies. Demonstrating high precision and accuracy.
Roche's next-generation PCR technology: LightCycler® PRO system
Designed to illuminate discoveries, from research to clinical diagnostics. Uncover the system’s innovative and empowering features!
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Overview
Product specification |
Value |
General characteristics |
|
Automation |
|
Remote monitoring |
Remote access to host computer for process monitoring and reviewing data |
Data management |
Compatibility with 21 CFR Part 11 |
Interfaces |
|
Temperature control |
Peltier-based heating/cooling from 20°C-99°C Integrated vapor chamber for optimal temperature distribution |
Heating rate |
96-well-block: 4.4 °C/s 384-well-block: 4.8 °C/s |
Filter |
7 Excitation 7 Emission |
Detector |
CMOS Camera |
Light source |
White LED lamp |
Dimensions and weight |
|
Instrument dimensions |
45.3 x 54.3 x 50.4 cm (W x H x D) |
Instrument weight |
54.5 kg |
Power supply |
|
Voltage |
100-240 VAC |
Line frequency |
50/60 Hz |
Explore the LightCycler® PRO system

Related products

Flexible and comprehensive molecular testing with Roche and TIB Molbiol
Expand your testing capabilities, confidently drive breakthroughs in healthcare, and respond to new biological threats with a broad menu of molecular assays and custom oligonucleotides.
*For research use only. Not for use in diagnostic procedures.
**Some assays are only available through TIB Molbiol or Roche. Assay availability varies by country. Contact your local representative for more information.
References
- F. Hoffmann-La Roche Ltd. LightCycler® PRO System SW1.2 User Guide 2.0. (v2.0). 2025.
- F. Hoffmann-La Roche Ltd. V&V Report: DH-02714.04-500B. Data on file.