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The MagNA Pure 96 System ensures purity, reproducibility, and laboratory efficiency for a successful molecular diagnostic workflow. Process up to 96 samples in less than one hour and increase your laboratory productivity to meet your changing needs.
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MagNA Pure 96 Kits are prefilled and ready-to-use reagent trays that can be easily loaded, ensuring ease of use and safety. Kits and consumables are barcoded and read by the MagNA Pure onboard scanner for inventory check, loading errors, and process documentation.
MagNA Pure 96 Software includes an intuitive graphical user interface, providing all instructions to operate the system, such as sample loading to run start. The software detects loading errors and provides information to the user for the appropriate corrective action.
Experience high throughput automation combined with high performance while increasing your laboratory productivity to meet your changing needs. Magnify your lab’s efficiency with seamless data management and expand your capacity for diverse day to day throughput needs.
IVD
Access package inserts through your country’s Roche Diagnostics website.
The MagNA Pure 96 System protocols are available for download from the table below (note: not available for download in the US).
Applications are very flexible, due to a diversity of software purification protocols using barcoded, prefilled trays with ready-to-use reagents.
MagNA Pure 96 kits are designed profiting from our more than ten year expertise in magnetic glass particle technology. We have streamlined the purification process to a very small number of reagents, consumables and steps.
Optimized preprogrammed purification protocols ensure routine sample handling and high quality, reproducible nucleic acid yields. Choose the appropriate purification protocol for your sample material and target nucleic acid.
| Target | Protocol name | Input sample type and sample volumes The latest version of MagNA Pure 96 protocols are available to download from the table below (not available in US) |
Elution volume | Run time*** (h:mm) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Whole blood | Plasma (citrate) | Plasma (EDTA) | Serum | Swabs | BAL* |
Sputum | CSF | Urine | Stool | Cultured cells | Fresh-frozen tissue | FFPET** | ||||
| Bacterial, fungal and viral NA | Pathogen Universal 200 1 | 200 μL | 50, 100 μL | 1:00 | ||||||||||||
| Fast Viral NA SV | 200 μL | 0:30 | ||||||||||||||
| Fast Viral NA ext lys SV | 450 μL lysate from 200 μL | 0:30 | ||||||||||||||
| Viral NA Plasma SV 1 | 50, 100, 200 μL | 1:00 | ||||||||||||||
|
Viral NA Plasma ext lys SV
1
Protocol optimized with external lysis reagent |
350, 450 μL lysate from 100, 200 μL sample | 1:00 | ||||||||||||||
| Viral NA Universal SV 1 | 50, 100, 200 μL | 50, 100, 200 μL | 1:00 | |||||||||||||
| Pathogen Universal 500 2 | 500 μL | 1:30 | ||||||||||||||
| Pathogen Universal 1000 2 | 1000 μL | 1:40 | ||||||||||||||
| Viral NA Plasma LV 2 | 500 μL | 1:10 | ||||||||||||||
| Viral NA Plasma LV 1000 2 | 1000 μL | 1:20 | ||||||||||||||
|
Viral NA Plasma ext lys LV
2
Protocol optimized with external lysis reagent |
1000 μL lysate from 500 μL sample | 1:10 | ||||||||||||||
| Viral NA Universal LV 2 | 500 μL | 500 μL | 1:30 | |||||||||||||
| Viral NA Universal LV 1000 2 | 1000 μL | 1000 μL | 1:30 | |||||||||||||
| Genomic DNA |
DNA Blood SV
1
Recommended for elution of predominantly double-stranded DNA |
50, 100 or 200 μL ≤ 2x106 cells/samples | 50, 100 μL | 1:00 | ||||||||||||
|
DNA Blood ext lys SV
1
Protocol optimized with external lysis reagent |
300, 350, or 450 μL lysate from 50, 100, 200 μL sample |
0:50 | ||||||||||||||
| DNA Cells SV 1 | Up to 5x105 cultured cells in 200 μL PBS | 100 μL | 1:00 | |||||||||||||
| DNA Tissues SV 1 | Up to 5 mg in 200 μL | 100, 200 μL | 1:20 | |||||||||||||
| DNA FFPE SV 1 | 200 μL lysate from 2x5 μL sections | 50, 100 μL | 1:00 | |||||||||||||
| DNA Blood LV 2 | 500 μL (≤ 1x107 cells/ml) | 100, 200 μL | 1:20 | |||||||||||||
| DNA Blood LV 1000 2 | 1000 μL (≤ 1x107 cells/ml) | 1:30 | ||||||||||||||
|
DNA Blood ext lys LV
2
Protocol optimized with external lysis reagent |
1000 μL lysate from 500 μL sample (≤ 1x107 cells/ml) | 100, 200 μL | 0:50 | |||||||||||||
| DNA Cells LV 1 | Up to 1x106 cultured cells in 200 μL PBS | 100, 200 μL | 1:20 | |||||||||||||
| DNA Tissue LV 2 | Up to 25 mg in 200 μL | 200 μL | 1:20 | |||||||||||||
| Cell-free NA |
cfNA ss 2000
2
Protocol optimized for single-stranded DNA |
2000 μL | 50, 100 μL | 2:00 | ||||||||||||
|
cfNA ss 4000
2
Protocol optimized for single-stranded DNA |
4000 μL | 2:20 | ||||||||||||||
|
cfNA ds 2000
2
Protocol optimized for double-stranded DNA |
2000 μL | 100, 200 μL | 2:20 | |||||||||||||
|
cfNA ds 4000
2
Protocol optimized for double-stranded DNA |
4000 μL | 2:50 | ||||||||||||||
| Total RNA | Cellular RNA LV 3 | Up to 1x106 cultured cells in 200 μL PBS | 50, 100, 200 μL | 1:30 | ||||||||||||
| RNA Blood LV 400 3 | 900 μL stabilized whole blood from 400 μL whole blood | 50, 100, 200 μL | 1:30 | |||||||||||||
| RNA Blood LV 800 3 | 1800 μL stabilized whole blood from 800 μL whole blood | 100, 200 μL | 1:30 | |||||||||||||
| RNA PAXgene LV 3 | PAXgene pellet in 400 μL PBS | 100, 200 μL | 1:30 | |||||||||||||
| RNA PAXgene Half Tube LV 3 | Half PAXgene pellet in 200 μL PBS | 50, 100 μL | 1:30 | |||||||||||||
| RNA Tissue FF Standard LV 3 | Up to 10 mg in 350 μL | 50, 100, 200 μL | 1:30 | |||||||||||||
| RNA Tissue FF High LV 3 | Up to 25 mg in 700 μL | 100, 200 μL | 1:30 | |||||||||||||
| RNA Tissue FFPE LV 3 | 150 μL lysate from 2x5 μm sections | 50, 100 μL | 1:30 | |||||||||||||
| Liquid handling |
Sample Transfer
to the processing cartridge |
50 µL to 1000 µL | NA | |||||||||||||
|
Archive Plate Transfer
for archiving purposes |
5 μL to 200 μL | NA | ||||||||||||||
| PCR Setup with Mixing | NA | |||||||||||||||
| PCR Setup without Mixing | NA | |||||||||||||||
|
1 MagNA Pure 96 DNA and Viral NA Small Volume Kit (cat. no. 06 543 588 001) |
*BAL - Bronchoalveolar Lavage |
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