cobas^® liat CT/NG/MG

nucleic acid test

IVD

Physician consulting a patient following STI testing of CT, NG, and MGon the cobas Liat system

Lab-quality sexually transmitted infection test results in 20 minutes at the Point of Care¹

Every day, more than 1 million people worldwide acquire a curable sexually transmitted infection (STI).² Among the most common are Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Mycoplasma genitalium (MG).² If left untreated, these infections can lead to serious complications, including pelvic inflammatory disease (PID), urethritis, ectopic pregnancy, and infertility, as well as an increased risk of infection with HIV.²

STI signs and symptoms are often nonspecific and overlapping, with up to 90% of cases being asymptomatic.³ Additionally, multiple STIs can coexist in a single patient.³ Although CT, NG, and MG may present with similar symptoms, each requires a different treatment approach, making accurate diagnosis essential. Syndromic management, which often leads to over- or under-treatment, is considered a major driver of antimicrobial resistance (AMR).⁴

The only way to ensure effective treatment and combat AMR is through definitive diagnosis with accurate testing. PCR testing at the Point of Care with the cobas® liat CT/MG/NG delivers rapid, reliable results—providing clarity in as little as 20 minutes.¹ Fast and accurate diagnosis empowers individuals to take control of their sexual health, make informed decisions, and receive the right treatment.

Benefits at a glance

Results in just 20 minutes¹

Fast results support actionable treatment decisions and reduce the need for patient follow up.

Gold-standard PCR technology⁵

Bring the exceptional quality of centralized laboratory testing right to the patient’s Point of Care—ensuring accurate and timely diagnostic results where they are needed most.

Strategic connected control

Timely POC STI testing with lab-quality control through centralized connectivity.

How Point of Care STI testing makes a difference

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Here are some important situations where patients can benefit from Point of Care testing for STIs. These tests provide quick results, which help with fast diagnosis and treatment. This timely action is crucial for both the patient's health and for preventing the spread of infections.

Show video transcript

Meet Eric, Maria, and Louis. All three have something in common. A risk for a sexually transmitted infection or STI. Each would benefit from knowing their STI status as quickly as possible. One doesn’t even have any symptoms, but would rather test than guess.

Discover how easy it can be for them and their healthcare providers to get quick, confident, control over their sexual health with STI diagnostics at the Point of Care using the cobas® liat system.

Eric visits a clinic due to symptoms of urethritis or pain with urination and urethral discharge. He’s been worried about these symptoms and his urgent care doctor suspects an STI. Current guidelines would direct the urgent care team to treat this presentation of urethritis empirically, without waiting for lab results to return, which could take several days.

This treatment would include coverage for gonorrhea infection, which is a large and painful injection. Fortunately, the care team has a cobas liat system with STI solutions—so the care team can confirm within 20 minutes that Eric’s symptoms are being caused by a Mycoplasma genitalium infection.

Gold-standard NAAT/PCR technology delivers the quality of centralized lab testing at the patient Point of Care. Those fast, definitive results reduced the need for patient follow-up and no need for the large, painful injection to cover for the gonorrhea.

Signs and symptoms of different STIs can overlap and are often non-specific, but can have different treatments. That’s the case for Maria.

Maria is in a lot of distress. The ED medical team suspects an STI based on examining her. Current guidelines recommend confirming the cause of the infection with testing, before providing treatment, but this is very difficult in a busy emergency department. But the ED has a cobas liat system with STI solutions, so the medical team can conclusively diagnose and treat Maria’s chlamydia infection immediately, without having her wait many hours in the ED and reducing the burden on the team to follow up on positive test results.

Rapid PCR STI testing can differentiate your clinic by providing answers to patients and their partners who want to know their STI status right now. That’s the case for Louis. He doesn’t have symptoms but has just heard from a partner that they have been diagnosed with an STI, and so he might have it too. In 24 hours he leaves for an overseas vacation and he appreciates that in just 20 minutes he can know if he definitely needs treatment.

Testing positive for gonorrhea, Louis gets the appropriate targeted treatment he needs before leaving for vacation. This same-day diagnosis and treatment also eliminated the risk of loss to follow-up, giving both the patient and clinician peace of mind knowing they are getting and giving the right treatment.

Eric, Maria, and Louis all benefited from STI testing with the cobas liat system at the Point of Care.

In addition to regular and routine screening using lab NAAT testing via cobas® 5800, 6800, and 8800 systems, bring the confidence that comes from knowing “right now” to STI patients anywhere. This includes collaborating at the Point of Care in decentralized settings with primary and secondary care.

To help patients know if they have an STI as quickly as possible, provide testing with the cobas liat system at the Point of Care. You’ll get results in just 20 minutes, with the confidence of PCR accuracy and lab-quality, centralized control.

cobas liat CT/NG/MG clinical performance⁶

View Full Table

Sample type	Male urine		Vaginal swab		Female urine
	Sensitivity	Specificity	Sensitivity	Specificity	PPA	NPA
CT	97.3%	99.9%	98.2%	99.8%	94.9%	99.8%
NG	100.0%	99.9%	97.7%	99.8%	100.0%	99.9%
MG	97.1%	99.2%	95.2%	97.8%	93.0%	98.6%

cobas liat CT/NG/MG specifications

View Full Table

Instrument	cobas® liat analyzer
Targets	Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium
Sample type	Male and female urine, Vaginal swab
Collection media	cobas® PCR Media
Sample extraction	Fully automated and integrated
Technology	Real-time PCR
Control	Internal sample processing control, positive and negative controls
Time to result	~20 minutes
Reagents	Ready-to-use, pre-packed tube format
Registration	CE-IVD (NPT)

References

cobas® liat CT/NG/MG CE-IVD Instructions for Use, 10147563190-01EN, Rev. 1.0
WHO. STI Fact Sheets. [Internet; cited 2024 August]. Available from: https://www.who.int/news-room/fact-sheets/detail/sexually-transmitted-infections-(stis).
CDC. [Internet; cited 2024 March 3]. Available from: https://www.cdc.gov/std/saw/talktesttreat/default.htm.
Garrett NJ, et al. Beyond syndromic management: Opportunities for diagnosis-based treatment of sexually transmitted infections in low- and middle-income countries. PLoS One. 2018 Apr 24;13(4):e0196209.
Hansen et al. Clinical Performance of the Point-of-Care cobas Liat for Detection of SARS-CoV-2 in 20 Minutes: a Multicenter Study. J Clin Microbiol. 2021;59(2):e02811-20.
cobas® liat CT/NG/MG CE-IVD Instructions for Use, 10147563190-01EN, Rev. 1.0

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cobas^® liat CT/NG/MG

Lab-quality sexually transmitted infection test results in 20 minutes at the Point of Care¹

Benefits at a glance

How Point of Care STI testing makes a difference

cobas liat CT/NG/MG clinical performance⁶