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For in vitro diagnostic use. Nucleus Others MSH2 G219-1129 MMR RxDx-MMR IHC Panel IVD Normal Colon Colorectal Cells VENTANA® anti-MSH2 (G219-1129) Mouse Monoclonal Primary Antibody RTD001201 For use with the VENTANA MMR IHC Panel Mouse G219-1129 09607137001 MSH2 (G219-1129) MM PAB W US Export MSH2 (G219-1129) MM PAB 07613336206201 Reagents, kits 730-7160 Not Available Not Available 09498478001 VENTANA MSH2 (G219-1129) PAB-US Export J VENTANA MSH2 (G219-1129) PAB 07613336200209 Reagents, kits 780-7141 Not Available Not Available 08033684001 MSH2 (G219-1129) MM PAB-US Export VENTANA anti-MSH2 (G219-1129) Mouse Monoclonal Primary Antibody 07613336119372 Reagents, kits 760-5093 50 tests Not Available true VENTANA anti-MSH2 (G219-1129) Mouse Monoclonal Primary Antibody (VENTANA anti-MSH2 (G219-1129) antibody) is intended for the qualitative detection of MSH2 protein in formalinfixed, paraffin-embedded tissue sections. VENTANA anti-MSH2 (G219- 1129) antibody is ready to use on BenchMark IHC/ISH instruments with the OptiView DAB IHC Detection Kit and ancillary reagents.VENTANA anti-MSH2 (G219-1129) antibody is part of the VENTANA MMR IHC Panel which includes VENTANA anti-MLH1 (M1) Mouse Monoclonal Primary Antibody, VENTANA antiPMS2 (A16-4) Mouse Monoclonal Primary Antibody, VENTANA antiMSH6 (SP93) Rabbit Monoclonal Primary Antibody and VENTANA antiBRAF V600E (VE1) Mouse Monoclonal Primary Antibody. The VENTANA MMR IHC Panel is indicated for the detection of mismatch repair protein deficiency as a test for the identification of individuals at risk for Lynch syndrome in patients diagnosed with colorectal cancer (CRC), and, with BRAF V600E status, as an aid to differentiate between sporadic and probable Lynch syndrome CRC in the absence of MLH1 protein expression.These products should be interpreted by a qualified pathologist in conjunction with histological examination, relevant clinical information, and proper controls.Intended for in vitro diagnostic (IVD) use. en VENTANA anti-MSH2 (G219-1129) antibody binds to MSH2 protein in formalin-fixed, paraffin-embedded (FFPE) tissue sections. The antibody can be localized using a haptenated secondary antibody followed by a multimer anti-hapten-HRP conjugate (OptiView DAB IHC Detection Kit). The specific antibody-enzyme complex is then visualized with a precipitating enzyme reaction product. Each step is incubated for a precise time and temperature. At the end of each incubation step, each BenchMark IHC/ISH instrument washes the sections to stop the reaction and to remove unbound material that would hinder the desired reaction in subsequent steps. It also applies ULTRA LCS (Predilute) or LCS (Predilute), which minimizes evaporation of the aqueous reagents from the specimen slide. en