For in vitro diagnostic use. Nucleus Others PMS2 A16-4 MMR RxD-MMR IHC Panel IVD Normal Colon Colorectal Cells VENTANA® anti-PMS2 (A16-4) Mouse Monoclonal Primary Antibody RTD001207 For use with VENTANA MMR RxDx Panel and the VENTANA MMR IHC Panel Mouse A16-4 09 498 486 001 9 498 486 001 09498486001 9498486001 09498486001 VENTANA PMS2 (A16-4) PAB-US Export J VENTANA PMS2 (A16-4) PAB 07613336200216 Reagents, kits 780-7142 Not Available Not Available 08 033 692 001 8 033 692 001 08033692001 8033692001 08033692001 PMS2 (A16-4) MM PAB-US Export VENTANA anti-PMS2 (A16-4) Mouse Monoclonal Primary Antibody 07613336119389 Reagents, kits 760-5094 50 tests Not Available true 09 607 161 001 9 607 161 001 09607161001 9607161001 09607161001 PMS2 (A16-4) MM PAB W US Export PMS2 (A16-4) MM PAB 07613336206218 Reagents, kits 730-7158 Not Available Not Available true VENTANA anti-PMS2 (A16-4) Mouse Monoclonal Primary Antibody (VENTANA anti-PMS2 (A16-4) antibody) is intended for the qualitative detection of PMS2 protein in formalinfixed, paraffin-embedded tissue sections. VENTANA anti-PMS2 (A16-4) antibody is ready to use on BenchMark IHC/ISH instruments with the OptiView DAB IHC Detection Kit, OptiView Amplification Kit, and ancillary reagents. VENTANA anti-PMS2 (A16-4) antibody is part of the VENTANA MMR IHC Panel which includes VENTANA antiMLH1 (M1) Mouse Monoclonal Primary Antibody, VENTANA anti-MSH2 (G219- 1129) Mouse Monoclonal Primary Antibody, VENTANA anti-MSH6 (SP93) Rabbit Monoclonal Primary Antibody and VENTANA anti-BRAF V600E (VE1) Mouse Monoclonal Primary Antibody. The VENTANA MMR IHC Panel is indicated for the detection of mismatch repair protein deficiency as a test for the identification of individuals at risk for Lynch syndrome in patients diagnosed with colorectal cancer (CRC), and, with BRAF V600E status, as an aid to differentiate between sporadic and probable Lynch syndrome CRC in the absence of MLH1 protein expression. These products should be interpreted by a qualified pathologist in conjunction with histological examination, relevant clinical information, and proper controls. This antibody is intended for in vitro diagnostic (IVD) use. en The VENTANA anti-PMS2 (A16-4) antibody is a mouse monoclonal antibody raised against a recombinant PMS2 protein. The VENTANA anti-PMS2 (A16-4) antibody binds to the PMS2 protein in FFPE tissue sections. The antibody can be localized using a haptenated secondary antibody followed by a multimer anti-hapten-HRP conjugate (OptiView DAB IHC Detection Kit, Cat. No. 760-700 / 06396500001) and the OptiView Amplification Kit (Cat. No 760-099/ 06396518001 (50 test) or 860-099 / 06718663001 (250)). The specific antibody-enzyme complex is then visualized with a precipitating enzyme reaction product. Each step is incubated for a precise time and temperature. At the end of each incubation step, the BenchMark ULTRA instrument washes the sections to stop the reaction and to remove unbound material that would hinder the desired reaction in subsequent steps. It also applies to ULTRA LCS (Predilute) (Cat. No. 650-210 / 05424534001) or LCS (Predilute) (Cat. No. 650-010 / 05264839001), which minimizes evaporation of the aqueous reagents from the specimen slide.In addition to staining with VENTANA anti-PMS2 (A16-4) antibody, a second slide should be stained with the mouse monoclonal negative reagent, Negative Control (Monoclonal) (Cat. No. 760-2014 / 05266670001). The negative reagent control is used to assess background staining. en

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VENTANA^® anti-PMS2 (A16-4) Mouse Monoclonal Primary Antibody

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