Bringing flexible capabilities to support tissue research and development of diagnostics, Roche’s DISCOVERY staining platform provides a solution for scientists and research professionals who demand more than what conventional immunohistochemistry (IHC) and in situ hybridization (ISH) platforms have to offer.
The key components of the DISCOVERY tissue research solution are:
The DISCOVERY ULTRA is an open platform allowing access to third-party or custom reagents via user-fillable dispensers and the Universal Software. The expansive potential is available out of the box, tackling the most difficult staining challenges and enabling:
Multiplex immunohistochemistry (mIHC) enables the detection of multiple biomarker antigens on the same tissue section. Compared to single stains, simultaneous biomarker detection enables a greater understanding of the bio-spatial signatures critical to a holistic understanding of biology and new foundations in the clinical presentation of disease. The scientific questions that can be addressed by mIHC and multiplexing ISH are many and span clinical, translational, and basic research applications.
The Research and Development team at VENTANA have developed several new chromogens and fluorophores to expand ISH and IHC multiplexing and assay development.
The DISCOVERY ULTRA and Universal Software lead the way in the tissue research and development environments of leading pharmaceutical companies, Contract Research Organizations (CRO), and Academic Medical Centers.
References
