Colorectal IHC portfolio

Colorectal IHC assays

Deliver diagnostic confidence

 

Roche offers a robust menu of tools to aid in colorectal cancer diagnostics. The Roche portfolio of assays, including IHC diagnostic assays, deliver the high sensitivity and specificity pathology professionals need.

Fully-automated IHC/ISH staining

Roche antibodies are ready to use on the fully-automated VENTANA BenchMark IHC/ISH staining platforms, reducing the time-to-result and resources required with manual or semi-automated solutions.

MLH-1
MLH-1 (M1) Mouse Monoclonal Primary Antibody
 

MLH-1 (M1) Mouse Monoclonal Primary Antibody is used to qualitatively identify human DNA mismatch repair (MMR) protein MLH1, expressed in the nucleus of normal proliferating cells. Loss of MLH1 is associated with colorectal and other cancers.

  • Mouse monoclonal antibody
  • Deficient or low levels of MLH1 are associated with colorectal and other cancer
  • Fully automated
PMS2 (EPR3947) Rabbit Monoclonal Antibody
PMS2 (EPR3947) Rabbit Monoclonal Antibody
 

PMS2 (EPR3947) antibody is indicated as an aid in diagnostic determination of MSI-H tumors within the context of the patient’s clinical history and other diagnostic tests evaluated by a qualified pathologist or physician.

  • Rabbit monoclonal antibody
  • Aids in diagnostic determination of MSI-H tumors within the context of the patient’s clinical history and other diagnostic tests
  • Fully automated
MSH2 (G219-1129)
MSH2 (G219-1129) Mouse Monoclonal Antibody
 

MSH2 (G219-1129) This antibody is used as an aid in the identification of microsatellite instability within the context of an antibody panel, the patient’s clinical history, and other diagnostic tests evaluated by a qualified pathologist..

  • Mouse monoclonal antibody
  • Aids in the identification of microsatellite instability within the context of an antibody panel
  • Fully automated
CONFIRM anti-MSH6 (44)
CONFIRM anti-MSH6 (44) Mouse Monoclonal Antibody
 

CONFIRM anti-MSH6 (44) Mouse Monoclonal Antibody is used to qualitatively identify human DNA mismatch repair (MMR) protein MSH6, expressed in the nucleus of normal proliferating cells. Loss of MSH6 is associated with colorectal and other cancers.

  • Mouse monoclonal antibody
  • Deficient or low levels of MSH6 are associated with colorectal and other cancers
  • Fully automated
BRAF V600E (VE1)
BRAF V600E (VE1) Mouse Monoclonal Primary Antibody
 

BRAF V600E (VE1) Mouse Monoclonal Primary Antibody may be used to aid in the identification of the mutant protein, BRAF V600E.

  • Mouse monoclonal antibody
  • Aids in the detection of the BRAF V600E mutant protein
  • Fully automated
CDX-2 (EPR2764Y)
CDX-2 (EPR2764Y)
 

CDX-2 (EPR2764Y) is a caudal-related homeobox transcription factor whose expression in the adult is normally restricted to the intestinal epithelium. Loss of CDX-2 protein expression has been correlated with loss of differentiation in colorectal cancers. Anti-CDX-2 antibody has been useful in distinguishing gastrointestinal origin of metastatic adenocarcinomas and carcinoids.

  • Rabbit monoclonal antibody
  • Loss of CDX-2 protein expression has been correlated with loss of differentiation in colorectal cancers
  • Aids in distinguishing gastrointestinal origin of metastatic adenocarcinomas and carcinoids