Pre-eclampsia is a serious multi-system complication of pregnancy, occurring in 3-5% of pregnancies, and it is one of the leading causes of maternal and perinatal morbidity and mortality worldwide.1-3 The landmark multicentre, prospective study – PROGNOSIS (Prediction of short-term outcome in pregnant women with suspected pre-eclampsia study) – demonstrated that the Elecsys® sFlt-1/PlGF ratio test can aid in the short term prediction of pre-eclampsia and, together with other clinical information, enables clinicians to rule out pre-eclampsia with high confidence for at least 1 week.4-5