Test before you Treat

Take charge of antibiotic prescribing 
Test before you treat with the cobas® Liat® System

Stewardship begins with you: Learn why testing matters
Diagnose confidently with the cobas® Liat® System

Most upper respiratory tract infections are caused by viruses, where antibiotics have no beneficial effect. Studies from general practice have demonstrated high rates of unnecessary antibiotic prescribing for patients with these types of infections.2

Together with the assessment of signs and symptoms, testing before treatment is an important step in determining the appropriate course of action. While most testing options offer a tradeoff between speed and accuracy, the cobas® Liat®System brings timely and reliable testing where it’s needed most: the point of care.

The cobas® Liat® PCR System allows optimal treatment decisions to prevent antibiotic misuse.


Antibiotics used in medicine are largely prescribed by general practitioners.


Primary care accounts for 80–90% of all antibiotic prescriptions in Europe, and most are prescribed for respiratory tract infections.3

However, sometimes they are prescribed for conditions
antibiotics cannot treat.

Of adults seeking treatment for respiratory infections in the US, a study found more than two thirds of antibiotics were most likely prescribed inappropriately.4

Antibiotics have no beneficial effect when the patient has a viral infection.
Rapid tests like Roche’s PCR technology help reducing antibiotic overuse.


Antibiotic treatment is most effective when it's optimized.

A study reports a 45% reduction in antibiotic prescribing in adults using rapid tests rather than signs and symptoms checks.5

Advanced diagnostics can help practitioners make informed treatment decisions.

Increase diagnostic confidence with the cobas® Liat® System—avoid the need for healthcare professionals to question a result, or for patients to wait for one. Avoid the need to question a result, wait for answers or rely solely on empiric treatment.

Get detailed information about antibiotic prescribing in the US and antibiotic stewardship.

Stewardship starts here


Small, swift, simple, and secure

There is a need for quick, well-informed treatment decisions at the point of care. On-site rapid antigen tests may be fast, but also have a lower rate of accuracy and require confirmation of negative results. Lab cultures are highly accurate, but have a long turnaround time—from 4 hours to 5 days.

The cobas® Liat® System offers a unique combination of speed, sensitivity and specificity. With a growing number of assays featuring turnaround times of 20 minutes or less, this compact molecular solution supports effective clinical management.

Discover how simple PCR testing can be with cobas® Liat® System.

  1. Ventola, CL. The Antibiotic Resistance Crisis: Part 1: Causes and Threats. P T. 2015 Apr;40(4):277–283. 
  2. Bagger K, Nielsen AB, Siersma V, Bjerrum L. Inappropriate antibiotic prescribing and demand for antibiotics in patients with upper respiratory tract infections is hardly different in female versus male patients as seen in primary care. Eur J Gen Pract. 2015;21:118-123. doi: 10.3109/13814788.2014.1001361. 
  3. Llor C, Bjerrum L. Antimicrobial resistance: risk associated with antibiotic overuse and initiatives to reduce the problem. Ther Adv Drug Saf. 2014;5(6):229–241. doi: 10.1177/2042098614554919. 
  4. O’Neill J. Rapid Diagnostics: Stopping unnecessary use of antibiotics. Review on Antimicrobial Resistance. October 2015. 
  5. McIsaac WJ, Kellner JD, Aufricht P, Vanjaka A, Low DE. Empirical validation of guidelines for the management of pharyngitis in children and adults. JAMA. 2004;291:1587–1595.
    *Turnaround time varies by assay: cobas® Influenza A/B, 20 minutes; cobas® Influenza A/B & RSV, 20 minutes; cobas® Strep A, 15 minutes.