cobas b 101 system

One-stop solution for HbA1c, lipids, and CRP testing in the Primary Care Setting

Product image forcobas b 101 system

Easy and Safe operations


  • Direct blood application from a single finger stick with small volume
  • No calibration needed, maintenance and service-free, guidance by the graphical user interface (GUI)
  • Robust, maintenance-and calibration-free with a wide operating temperature and humidity range
  • Connection to cobas® infinity POC IT solutions
  • Data download to USB stick and then to a PC or data download to IT solutions installed on PC.



Save time


  • Connect the cobas b 101 system to your practice software and transfer test results directly to the electronic patient record.
  • Speed up and simplify tasks with identical procedures for all tests.
  • Use the tests without warming them up - no waiting time.
  • You can rest assured that the cobas b 101 system is maintenance-free and always ready for use.
  • Fast turnaround time: from patient preparation to displaying dual testing results in a less than 15-minute workflow and single testing results in about 6 minutes (CRP in less than 4 minutes)




Save Space


  • Store tests at room temperature and save space in the fridge.
  • Use the smallest test system in its class for CRP, HbA1c and lipids.

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cobas b 101 system complies with all relevant standards and methods (IFCC, DCCT/NGSP)1

cobas b 101 system

Product specifications

  • Sample size

    HbA1c: 2 μL
    Lipid: 19 μL
    CRP: 12 μL

  • Sample material

    Capillary whole blood, venous whole blood with anticoagulant (EDTA or heparin)
    HbA1c PST: 
    Capillary whole blood

    Capillary whole blood, venous whole blood or plasma with anticoagulant (EDTA)
    Lipid PST: 
    Capillary whole blood

    CRP: Capillary whole blood or serum, venous whole blood or plasma with anticoagulant (EDTA or heparin)


  • Measurement range

    20 - 130 mmol/mol (IFCC) or 4–14 % (DCCT/NGSP)


    CHOL: 50–500 mg/dL or 1.28–12.95 mmol/L
    TRIGL: 45–650 mg/dL or 0.50–7.35 mmol/L
    HDL-CHOL: 15–100 mg/dL or 0.38–2.60 mmol/L
    LDL-CHOL: estimated using the Friedewald equation


    3.0–400 mg/L or 0.30–40.0 mg/dL




  • Test storage

    2 to 30 °C

  • Test stability

    CRP Lipid: 16 months
    HbA1c: 22 months

    Opened: 20 minutes 










  1. Roche (2012). multi-center evaluation data on file.
  2. Roche (2019) cobas HbA1c Test, Method Sheet Version 2.0
  3. Roche (2019) cobas Lipid Panel, Method Sheet Version 5.0
  4. Roche (2019) cobas CRP Test, Method Sheet Version 2.0