cobas® c 111 analyzer

IVD For in vitro diagnostic use.
<b>cobas<sup>®</sup></b> c 111 analyzer

Small footprint. Big performance

The cobas® c 111 analyser is the smallest member of Roche’s cobas® core lab clinical chemistry platform family, delivering reliable results at a throughput of up to 85 tests per hour, with high accuracy and precision.1-6

With a small footprint of only 0.3m², the cobas c 111 analyser offers over 40 different tests, with the same reagent chemistry as the broader cobas® platform, combining compact convenience with diagnostic versatility.1

Designed for durability, it requires maintenance visits only once every 1.5 years.7 Roche’s proven technology is trusted by laboratories worldwide, with more than 6,700 active installations of the cobas c 111 across 125 countries.8

An instrument designed to fit in many ways

Illustration depicting the cobas® c 111 analyser as the main analyser within a small lab.

Routine

Perfectly suited as a main analyser for small labs, small hospitals and clinics, and satellite labs of larger networks.

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Illustration depicting the cobas® c 111 analyser as a backup analyser within a large lab.

Backup

Serves well as a backup analyser for larger cobas® clinical chemistry analysers.

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Illustration depicting the cobas® c 111 analyser as a dedicated analyser within an emergency or intensive care setting.

Dedicated

Used as a dedicated analyser for STAT samples in accident and emergency and intensive care departments by trained lab professionals, as well as for specialised testing, such as HbA1c-only analysis.

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Benefits at a glance

Benefits at a glance

Close-up of a lab technician inserting a reagent bottle into the cobas c 111 analyser.
  • Preparation of up to 8 different reagent disks adaptable to individual panel testing.
  • Each reagent disk can hold up to 27 bottles which allows for 13 different tests in one reagent disk Prepared reagent disks can be stored in a refrigerator until needed and with one disk on board (within the shelf life of the respective parameter).
Front view of the cobas c 111 analyser with water and waste containers visible on the right.

Independent and flexible water supply with 3 liter water and waste containers.

Link to high-res file or location in branding library https://drive.google.com/file/d/1XKTQfAUiB0K3CM63y8nt90ZhLdTmRrGz/view?usp=drive_link Image metadesription (125 characters max; see guidelines Close-up of a gloved lab technician’s hand interacting with the cobas c 111 analyser display screen.
  • Guiding software wizard for daily start-up and maintenance procedure.
  • 'Time to Result' indicator for predictable walk away time.
A gloved hand of a lab technician inserting a sample tube into the cobas c 111 analyser.
  • Easily load any sample tube type into the sample loading area, without the need for manual configuration.
  • Experience uninterrupted workflow with continuous sample loading (up to 60 cuvettes), eliminating the need to stop the instrument for new samples.
Lab technologist scans a reagent for the cobas c 111.
  • Same reagents used for cobas® c packs and cobas® c 111 reagent bottles, delivering comparable results across the cobas platform.
  • Same calibrators and controls available for all cobas® clinical chemistry analysers.

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Overview

Ordering Information

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Product specification Value
Physical dimensions Width: 590 mm
Depth: 550 mm
Height: 480 mm
Weight: 32 kg
Test throughput

Photometric:
85 tests/h max
60 tests/h consolidated
(with typical test panel).

ISE:
180 tests/h max
60-100 tests/h consolidated
(photometric and ISE mixed).
Time to first result

Photometric:
5 – 10 min

ISE:
2 min
Sample types Serum, plasma, urine, whole blood (HbA1c)
Sample input

Continuous loading of primary and secondary tubes into 8 sample positions

Priority STAT sampling

Technical Documents

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Explore the cobas 111 analyser

Image of the cobas® c 111 analyser with key components highlighted.

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    Contact us

    Do you have questions about our products or services? We’re here to help. Contact a Roche representative in your region.

    References

    1. F. Hoffmann-La Roche Ltd. cobas® c 111 analyzer User Guide Version 4.5 Software Version 4.3 or higher. (v1). 2023.
    2. F. Hoffmann-La Roche Ltd. cobas® c 311 analyzer Operator's Manual Version 3.2 Software Version 01-13. (v3.1). 2023.
    3. F. Hoffmann-La Roche Ltd. cobas® pure integrated solutions User Guide Software Version 01-05. (v2.3). 2024.
    4. F. Hoffmann-La Roche Ltd. cobas® pro integrated solutions User Guide Software Version 03-02. (v4.1). 2025.
    5. F. Hoffmann-La Roche Ltd. Calculated method comparison of cobas c 501 vs. cobas c 111. Data on file. 2023.
    6. F. Hoffmann-La Roche Ltd. Measured method comparison of cobas c 503 vs. cobas c 111. Data on file. 2023.
    7. F. Hoffmann-La Roche Ltd. GCS Product Report for Instruments, Executive Summary. Data on file. 2023.
    8. F. Hoffmann-La Roche Ltd. ICB Instrument Dashboard - Number of countries and installations. Data on file. 2024.