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Influenza

Help stop the spread of influenza

Influenza is a seasonal respiratory illness that occurs annually, usually peaking in winter. It affects 5-10% of adults and 20-30% of children each year.1 Seasonal outbreaks can result in hospitalisation and death mainly among high-risk groups (the very young, elderly or chronically ill).2 Worldwide, annual epidemics are estimated to result in 3–5 million cases of severe illness, and 290,000–650,000 deaths.2

Annual Global Incidence Graphic

Roche’s influenza portfolio

Influenza A/B and RSV molecular point of care test

Automated multiplex real-time RT-PCR assay for the rapid in vitro qualitative detection and discrimination of Influenza A virus, Influenza B virus and respiratory syncytial virus (RSV) RNA ~20 minutes.

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High-volume SARS-CoV-2 & Influenza A/B test

Reliable and high-quality results for clinical decision-making for the improved management of COVID-19.

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SARS-CoV-2 & Influenza A/B molecular point-of-care test

Multiplex detection and differentiation of SARS-CoV-2, influenza A and influenza B in 20 minutes from a single nasal sample.

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References

  1. WHO (2012). World Health Organization. Vaccines against influenza. WHO position paper. Weekly Epidemiol Record. 87(47):461–76.
  2. WHO (2018). Influenza (seasonal) factsheet. Available at http://www.who.int/mediacentre/factsheets/fs211/en/ last access 03 May 2021
  3. Mayo Clinic (2016), Symptoms and causes. Available at http://www.mayoclinic.org/diseases-conditions/flu/symptoms-causes/dxc-20248062 last access 03 May 2021
  4. Call, S.A., Vollenweider, M.A., Hornung, C.A., Simel, D.L., McKinney, W.P. (2005). Does this patient have influenza? JAMA 293(8), 987-997.
  5. CDC (2016). Guidance for Clinicians on the Use of Rapid influenza diagnostic tests. Available at http://www.cdc.gov/flu/professionals/diagnosis/clinician_guidance_ridt.htm#figure1 last accessed 04 May 2021
  6. CDC (2019). Information on Rapid Molecular Assays, RT-PCR, and other Molecular Assays for Diagnosis of Influenza Virus Infection. Available at https://www.cdc.gov/flu/professionals/diagnosis/molecular-assays.htm last accessed on 19 Jul 2021.
  7. Caliendo, A., et al. (2013). Better tests, better care: improved diagnostics for infectious diseases. Clin Infect Dis 57(3), S139-170.
  8. Brooke-Pearce, F., Demertzi E. (2019). Introduction of cobas Liat Influenza A/B for rapid point-of-care diagnosis of influenza infection in an acute trust.  Infect Prev 20(6):297-300.  https://doi.org/10.1177/1757177419853342
  9. Benirschke RC, McElvania E, Thomson RB, Kaul KL, Das S. Clinical Impact of Rapid Point-of-Care PCR Influenza Testing in an Urgent Care Setting: a Single-Center Study. J Clin Microbiol. 2019;57(3)..
  10. Perlitz B, Slagman A, Hitzek J, Riedlinger D, Möckel M. Point‐of‐care testing for influenza in a university emergency department: A prospective study. Influenza Other Resp. 2021.
  11. Rogan DT, Kochar MS, Yang S, Quinn JV. Impact of Rapid Molecular Respiratory Virus Testing on Real-Time Decision Making in a Pediatric Emergency Department. J Mol Diagnostics. 2017;19(3):460–7.