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Roche Digital Pathology Open Environment

Pathology is undergoing a transformation towards digitization. The need for a pathology workflow solution that can enable pathologists to efficiently complete their daily workload and enable easy access to new digital tools is essential for wider adoption. Roche Digital Pathology expands its commitment to improving patient outcomes and advancing personalized healthcare through open environment innovation.

As artificial intelligence tools for clinical use continue to develop, industry and research partners can now leverage Roche’s Open Environment. This access expands the ability for pathologists to more easily read images from the VENTANA DP 200 slide scanner1 for image analysis algorithm development. It also allows for partnerships between researchers and developers, which can result in greater access to innovative imaging tools for laboratories and healthcare providers. 

To further grow the Digital Pathology Open Environment, Roche is building an Open API (application programming interface) framework to enable third-party companies to deploy their algorithms within Roche uPath enterprise software1. Innovative pathology imaging tools based on artificial intelligence can ultimately support the selection of the most appropriate targeted therapy option for each patient, advancing the Roche mission to deliver personalized healthcare.

If you are developing your own digital pathology image analysis algorithms and interested in learning more about how to use the Roche Open API, please click below.

Roche Digital Pathology BIF image file format2

With the acceleration of immunotherapy and the development of more complex assays, Roche would like to encourage the development of reliable image analysis algorithms that can provide pathologists with tools to improve efficiency and precision for diagnosis. To that end, Roche is making the specification of the Roche proprietary BIF file format publicly available, subject to Roche terms and conditions.

The BIF file format is based on the BigTIFF format; it supports single-wide and double-wide slides at 20x and 40x magnifications with varying tile overlaps. BIF also encapsulates information about which slide areas actually contain tissue. The specifications include a detailed description of the Roche proprietary metadata in BIF and may provide sufficient information to software developers to allow for the implementation of BIF file readers.

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1 The VENTANA DP 200 slide scanner and Roche uPath enterprise software are CE-IVD marked for in-vitro diagnostic use and are available in the U.S. for research use only (RUO). Image analysis algorithms developed by third-party entities and their utilisation are the responsibility of the third party provider.

2 Only for the VENTANA DP 200 slide scanner