A biomarker for the management of ovarian cancer patients
The Roche Elecsys® HE4 assay is a tumor marker test for use with blood samples to support monitoring and surveillance of ovarian cancer patients and together with Elecsys® CA 125 II for risk assessment of patients with pelvic mass with the ROMA™ algorithm.
Human epididymal protein 4 (HE4) is a biomarker that is highly elevated in epithelial ovarian cancer and has been shown to be involved in ovarian cancer cell proliferation and invasion1-3
HE4 has a higher sensitivity and specificity than CA 125 in the detection of ovarian cancer in patients presenting with pelvic mass4
In addition, HE4 can be used for monitoring disease and progression.8-10