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Neurology

Neurological disorders are an important cause of disability and death worldwide.1

 

Globally, the burden of neurological disorders has increased substantially over the past 25 years because of expanding population numbers and ageing, despite substantial decreases in mortality rates from stroke and communicable neurological disorders.1

The number of patients who will need care by clinicians with expertise in neurological conditions will continue to grow in coming decades.2

 

Biomarkers for neurological disorders are urgently needed3

 

Neurological disorders, such as Alzheimer’s disease and other dementias, brain injury, Parkinson’s disease and others, would ideally exhibit a unique pathology to allow clinicians to distinguish particular conditions and give a reliable diagnosis and treatment.3

In reality, however, many neurodegenerative diseases share similar symptoms and features and the task of diagnosis is often challenging.3

Biomarkers are urgently needed to aid diagnosis, monitor disease progression and as new medicines are introduced, detect the patient’s response to treatment.3

 

References

 

  1. Tarun Dua et al. Neurological disorders. Public health challenges, Geneva, World Health Organization Press, 2006.
  2. Valery L Feigin et al. The Lancet Neurology, 2017, 16 (11): 877-897
  3. Ward M. et al. Therapy, 2010, 7(4): 321–336
  4. Alzheimer’s Disease International. World Alzheimer Report 2018. Available at:https://www.alz.co.uk/research/WorldAlzheimerReport2018.pdf
  5. https://www.alzheimer-europe.org/Research/Value-of-Knowing
  6. https://www.who.int/news-room/fact-sheets/detail/dementia
  7. Jack CR Jr, et al. Lancet Neurol 2010;9:119–28
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