Determining HCV genotype
The determination of hepatitis C virus (HCV) genotype prior to treatment initiation has been implemented in international HCV treatment guidelines.1-3
cobas® HCV GT is a highly sensitive, real-time PCR based test for the qualitative identification of HCV genotypes 1 to 6 and genotype 1 subtypes A and B in human plasma or serum from individuals with chronic HCV infection, using the cobas® 4800 System.4
cobas® HCV GT uses three different target regions in the HCV genome (5’-UTR, Core, NS5B) to achieve excellent genotyping and subtyping accuracy compared to sequencing and the capability to detect both genotypes in mixed infections down to a ratio of 1:100.4