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System Accessories & Disposables", "StructureGroupName": "FLOW System Accessories & Disposables" }, { "IdentifierofStructureSystem": "OWP_Product_Types", "NameofStructureSystem": "Product Types", "StructureNodeID": "50-000-00", "StructureGroupPath": "Consumables", "StructureGroupName": "Consumables" }, { "IdentifierofStructureSystem": "Lab_Type", "NameofStructureSystem": "Lab Types", "StructureNodeID": "150-00", "StructureGroupPath": "Research Lab", "StructureGroupName": "Research Lab" }, { "IdentifierofStructureSystem": "Product_Solutions", "NameofStructureSystem": "Product Solutions", "StructureNodeID": "100", "StructureGroupPath": "Molecular", "StructureGroupName": "Molecular" }, { "IdentifierofStructureSystem": "Lab_Type", "NameofStructureSystem": "Lab Types", "StructureNodeID": "170-00", "StructureGroupPath": "LifeScience", "StructureGroupName": "LifeScience" }, { "IdentifierofStructureSystem": "Applications", "NameofStructureSystem": "Applications", "StructureNodeID": "99-00-00", "StructureGroupPath": "NOT APPLICABLE", "StructureGroupName": "NOT APPLICABLE" }, { "IdentifierofStructureSystem": "OWP_Techniques", "NameofStructureSystem": "Techniques", "StructureNodeID": "999-00", "StructureGroupPath": "NOT APPLICABLE", "StructureGroupName": "NOT APPLICABLE" }, { "IdentifierofStructureSystem": "Disease_Areas", "NameofStructureSystem": "Disease Areas", "StructureNodeID": "99-00-00", "StructureGroupPath": "NOT APPLICABLE", "StructureGroupName": "NOT APPLICABLE" }, { "IdentifierofStructureSystem": "Pathogens", "NameofStructureSystem": "Pathogens", "StructureNodeID": "99-00-00", "StructureGroupPath": "NOT APPLICABLE", "StructureGroupName": "NOT APPLICABLE" }, { "IdentifierofStructureSystem": "OWP_Family", "NameofStructureSystem": "Product Families", "StructureNodeID": "999", "StructureGroupPath": "NOT APPLICABLE", "StructureGroupName": "NOT APPLICABLE" }, { "IdentifierofStructureSystem": "Health_Topics", "NameofStructureSystem": "Health Topics", "StructureNodeID": "99-00-00", "StructureGroupPath": "NOT APPLICABLE", "StructureGroupName": "NOT APPLICABLE" } ] } ] }, "ProductSpec": [ { "ProductSpecVariant": { "Chapters": [ { "Language": "es", "Value": "El MagNA Pure 24 System es un sistema de purificación de ácidos nucleicos automatizado compuesto por el MagNA Pure 24 Instrument y el software, el material fungible y los reactivos correspondientes. El MagNA Pure 24 System está diseñado para el uso por parte de usuarios profesionales en la purificación de ácidos nucleicos a partir de muestras biológicas con fines de diagnóstico in vitro.", "Country": "XG", "Code": "Intended Use", "Name": "Intended Use" }, { "Language": "en", "Value": "About run types and workflows

The MagNA Pure 24 System offers 4 run types:

Purification (rack) run
In a purification (rack) run, the instrument pipettes sample material from sample tubes, processes it, and transfers the eluates to the output consumables in the cooling station.
The purification (rack) run is the fully automated combination of a sample transfer run and a purification (cartridge) run.

Purification (cartridge) run
In a purification (cartridge) run, the processing cartridges are pre-filled with sample material, either in a previous sample transfer run, or by manual pipetting. The instrument processes the sample material, and transfers the eluates to the output consumables in the cooling station.
In the case of a previous sample transfer run, open the corresponding order to load sample details.

Post elution run
In a post elution run, the instrument pipettes eluates into 8-tube strips (either empty or containing manually prepipetted PCR master mix reagent). From each eluate, the instrument pipettes up to 2 eluate aliquots. Additionally, the instrument pipettes controls. Sample information from a previous purification run is loaded when reading the barcodes of the eluate output consumables.
A post elution run uses the cooling station only and requires a dedicated post elution adapter.

Sample transfer run
In a sample transfer run, the instrument pipettes sample material from sample tubes into processing cartridges.
You can then use the sample-filled processing cartridges in a purification (cartridge) run.

The run types differ in input and output and use different instrument stations.(see Fig. 2).
 
", "Country": "XG", "Code": "Principle", "Name": "Principle" }, { "Language": "en", "Value": "For safety related information refer to the MagNA Pure 24 Safety Manual.

Chemical reaction producing toxic gas
Mixing bleach or DNA AWAY™ Surface Decontaminant with reagents can result in a chemical reaction that produces a highly toxic gas.
-> Do not allow reagents containing guanidine thiocyanate to contact sodium hypochlorite (bleach) solution or acids.
See also the reference from the FDA: Transport Media Safety Risk - Use Compatible Transport Media with SARS-CoV-2 Tests that Use Bleach - Letter to Clinical Laboratory Staff and Health Care Providers.", "Country": "XG", "Code": "Safety Information", "Name": "Safety Information" }, { "Language": "en", "Value": "The MagNA Pure 24 System is a fully automated clinical sample extractor. It extracts nucleic acids from various sample types, sample tubes, and volume inputs for multiple downstream applications.
The main features of the system are:

  • Scalable purification of 1 to 24 samples
  • Primary/secondary tube handling
  • Inventory and sample management via barcodes
  • Efficient order management via host
", "Country": "XG", "Code": "Product Description", "Name": "Product Description" }, { "Language": "en", "Value": "1. MagNA Pure 24 Instrument
2. Built-in control unit with preinstalled MagNA Pure 24 operating software and purification protocols
3. MagNA Pure 24 Accessories
4. Digital User Assistance", "Country": "XG", "Code": "Content", "Name": "Content" } ] } } ] }

MagNA Pure 24

Empieza aquí. Ve a cualquier parte.

Product image for MagNA Pure 24 System

Adéntrate en un nuevo mundo de productividad

 

Empieza aquí. Llega donde quieras.

 

Durante años, los laboratorios de biología molecular han confiado en la familia de productos MagNA Pure para reducir los errores de tratamiento de muestras, gracias a la preparación de muestras fiable y simplificada que ofrece esta gama de productos. En consonancia con este legado, el sistema MagNA Pure 24 es un sistema clínico de extracción de ácidos nucleicos totalmente automatizado que proporciona una automatización sin necesidad de supervisión, diseñado para reducir la intervención del usuario y la variabilidad entre extracciones.

Purificación sin esfuerzo, confianza en la automatización

  • Rendimiento probado que realiza análisis reproducibles y estables
  • Extracción escalable de 1 a 24 muestras con tratamiento de muestra primaria en solo una hora.
  • Un único set de reactivos universal con 10 tipos de muestras humanas con volúmenes de entrada de entre 200 μl a 4 ml
  • Trazabilidad completa con un inventario y seguimiento de muestras a través de la lectura del código de barras
  • Automatización real, sin necesidad de supervisión
  • Prevención de la contaminación mediante una lámpara UV integrada y tecnología CO-RE Tip

 

Lote con reactivos listos para usar, precargado y con código de barras

 

El set universal de ácidos nucleicos totales MagNA Pure 24 elimina la complejidad innecesaria y permite una extracción eficiente de ácidos nucleicos de 10 tipos de muestras humanas previamente validados con un set de reactivos universal. Sella los cassettes de reactivos para un uso posterior y deja que el sistema identifique y realice el seguimiento del uso del reactivo con el lector de código de barras integrado.

 

Flexibilidad para poder hacer más

 

El sistema MagNA Pure 24 te ofrece flexibilidad para extraer hasta 10 tipos de muestras humanas diferentes con un único set de reactivos universal. Confía en este concepto simplificado de reactivos y selecciona uno de los protocolos previamente optimizados y programados para realizar extracciones a partir de tipos de muestras distintas y tubos primarios en un mismo set con un solo protocolo.  

 

La eficiencia simplificada

El sistema MagNA Pure 24 no solo es un sistema automatizado. Además, permite ausentarse durante la ejecución de la prueba gracias a una sencilla supervisión a través de un código de barras y una interacción mínima del usuario, para reducir el número de errores humanos y ahorrar tiempo.

 

  • Configuración de extracción sencilla
  • Interfaz de usuario intuitiva y guiada en la pantalla táctil integrada
  • Ejecuta el protocolo rápido con hasta 8 muestras en un máximo de 30 minutos
  • Comprobación de carga de menos de 30 segundos antes de la ejecución.
  • Primer encendido del día rápido (<5 minutos)
  • Gestión de datos sin interrupciones a través de la conectividad LIS
  • Extracción de muestras FFPET totalmente automatizada con desparafinación y lisis incorporadas

 

Confianza integrada

 

En las pruebas moleculares es esencial tener confianza en el eluido. El sistema MagNA Pure 24 es un dispositivo IVD/CE-IVD con funciones de supervisión integradas para garantizar la más alta calidad de los eluidos y disminuir el número de errores humanos.

 

  • Funciones de control de seguridad y contaminación
  • Seguimiento de la identificación de las muestras y del uso de reactivos mediante lectura de código de barras.
  • Bloque de refrigeración para la preservación de los eluidos
  • Trazabilidad del software con una traza de gestión de auditoría
  • Archivado de datos generados con el software del sistema; comprueba los datos archivados con el visor de archivado autónomo del PC
  • El sistema Magna Pure 24 ejecuta actualmente la versión 1.2 del software

Estado de registro

IVD

Vídeo técnico del sistema MagNA Pure 24

Prospectos

Accede a los prospectos a través del sitio web de Roche Diagnostics de tu país.

Descargar protocolos

 

El nuevo paquete 3.0 de protocolos del sistema MagNA Pure 24 puede descargarse en la tabla siguiente (nota: no disponible para su descarga en EE. UU.).

 

Protocolos del sistema MagNA Pure 24

 

Datos guardados con éxito
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text
Diana  Nombre del protocolo Introduzca el tipo de muestra y los volúmenes de muestra  Volumen de elución  Tiempo de proceso♰ (h:mm)
 Sangre entera  Plasma  Suero Hisopos nasales*  LBA**
 Orina  Heces  Células cultivadas Tejido fresco-congelado FFPET***
Ácido nucleico bacteriano, micótico y vírico Patógeno 200  

Protocolo optimizado para velocidad

200 μl   50 o 100 μl 1:22
Patógeno rápido 200  

Protocolo de 8 muestras optimizado para velocidad, rendimiento y pureza

  0:35
Patógeno 1000

Protocolo optimizado para rendimiento y pureza

500 o 1000 μl   1:40
Patógeno de lisis externa 200
Patógeno de lisis externa 500  

Protocolos optimizados con tampón de lisis externa

450 μl de lisado de una muestra de 200 μl
1450 μl de lisado de una muestra de 500 μl
  1:30
1:40
ADN genómico hgDNA 200  

Protocolo optimizado para NA genómico humano

200 μl (≤ 2x106 células)   Hasta 5 x 105 Hasta 5 mg   1:15
hgDNA 200 rápido  

Protocolo de 8 muestras optimizado para velocidad

  0:25
hgDNA ds 200  

Protocolo optimizado para NGS

1:15
hgDNA 1000  

Protocolo optimizado para rendimiento y pureza

500 μl (≤ 5x106 células)
1000 μl (≤ 1x107 células)
100 o 200 μl 2:25
Hasta 1 x 106
ADN de FFPET 1000  

Desparafinación y lisis incorporadas

  Hasta 6 secciones de 5 μm (hasta 6 mm3) 50 o 100 μl 5:30
Ácido nucleico sin células cfNA ss 2000
cfNA ss 4000  

Protocolo optimizado para ADN monocatenario

  2000 μl   50 o 100 μl 2:05
4000 μl 3:00
cfNA ds 2000
cfNA ds 4000  

Protocolo optimizado para ADN bicatenario

  2000 μl   100, 150 o 200 μl 2:30
4000 μl 3:30
cfNA ds 4000 hp  

Protocolo optimizado para ADN bicatenario y NGS

  4000 μl   60 o 150 μl 4:40
Postelución Transferencia de muestras   al cartucho de procesamiento 200 μl
500 μl
1000 μl
  0,08
Configuración de la PCR   para 2-25 μl por eluido para configuración de PCR en en Frame-Strip con tiras de 8 tubos LightCycler® o de perfil bajo y tapones planos   0,05
Archivado   para 2-25 μl por eluido para configuración de PCR en en FrameStrip tiras de perfil bajo o tiras de 8 tubos LightCycler® 0,05
Nuevo protocolo
*Hisopos nasales/nasoofaríngeos
**LBA: lavado broncoalveolar
***FFPET: tejido fijado con formalina y embebido en parafina
♰Estos tiempos son aproximados y solo deben utilizarse como guía.

Resumen

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