For in vitro diagnostic use. Others CINtec PLUS Kit IVD Cervical Carcinoma CINtec® PLUS Kit RTD001246 CE-IVD Mouse Rabbit p16: E6H4™ mouse monoclonal antibody, Ki-67: 274-11 AC3 rabbit monoclonal antibody 06 595 367 001 6 595 367 001 06595367001 6595367001 06595367001 CINtec PLUS Cytology Kit (CE/IVD) CINtec PLUS Cytology Kit 04015630983889 Reagents, kits 50 tests Not Available false 10 215 348 001 10215348001 CINtec PLUS Cytology Kit (CE/IVD) CINtec PLUS Cytology Kit 07613336230374 Reagents, kits 50 tests Not Available false El CINtec® PLUS Kit es un ensayo inmunocitoquímico para determinar cualitativa-mente y de manera simultánea las proteínas p16INK4a y Ki-67 en preparaciones citológicas cervicales.El uso de este kit está previsto como ayuda en la identificación de mujeres con lesiones intraepiteliales de alto grado, tanto en cribado primario como en el sub-grupo de las pacientes que tienen un resultado de citología de ASCUS (células escamosas atípicas de significado indeterminado), LSIL (lesiones escamosas in-traepiteliales de bajo grado) o pacientes con resultados positivos a un test de VPH de alto riesgo.El uso de este kit está previsto para laboratorios de citología. La interpretación de los resultados debe realizarla un profesional certificado basándose en la historia clínica del paciente y en otras pruebas diagnósticas realizadas.La prueba está diseñada para su uso manual o para su uso en los instrumentos Autostainer. es The CINtec® PLUS Kit contains a set of reagents for the immunocytochemical detection of the p16INK4a and Ki-67 antigens. The kit is designed to perform a two-step immunocytochemical staining procedure for cytological specimens obtained from the cervix uteri. For the detection of the antigens, a primary monoclonal mouse an-tibody clone E6H4™ directed to human p16INK4a protein and a primary monoclonal rabbit antibody clone 274-11 AC3 directed against human Ki-67 protein are used.Ready-to-use visualization reagents comprising (i) a polymer reagent conjugated to horseradish peroxidase and goat anti-mouse Fab’ antibody fragments, and (ii) a polymer reagent conjugated to alkaline phosphatase and goat anti-rabbit Fab’ antibody fragments are used. The visualization reagents have been subjected to solid-phase absorption to eliminate cross reactivity with human immunoglobulins.The chromogen reactions are based on horseradish peroxidase-mediated conver-sion of a DAB chromogen, and alkaline phosphatase-mediated conversion of Fast Red chromogen to visible reaction products at the respective antigen sites. After counterstaining, a two step mounting protocol must be applied: in a first step, an aqueous mounting of the specimens using an aqueous mounting medium provided with the kit must be used. Subsequently, the slides may be cover-slipped using e.g. a permanent mounting medium. The results can be evaluated by light microscopy inspection. en

User profile

Select your user profile

CINtec^® PLUS Kit

Resumen

Pedidos

Documentos técnicos

Instrumentos compatibles

Productos relacionados

Contacta con nosotros

User profile

Select your user profile

CINtec® PLUS Kit

Related portfolios

Resumen

Pedidos

Documentos técnicos

Instrumentos compatibles

Productos relacionados

Contacta con nosotros

CINtec^® PLUS Kit