For in vitro diagnostic use. Others LumiraDx INR IVD LumiraDx INR PID00000894 10 443 065 001 10443065001 LumiraDx INR Test (48T) ML03 LumiraDx INR Test (48T) ML03 05060537711430 Reagents, kits L003000104048 48 tests Not Available undefined Las Tiras Reactivas LumiraDx INR están indicadas para utilizarse con el LumiraDx Instrument. Deben ser utilizadas por profesionales sanitarios para el análisis cuantitativo del tiempo de protrombina, notificado como Razón Normalizada Internacional (International Normalized Ratio, INR), para la vigilancia del tratamiento anticoagulante oral con antagonistas de la vitamina K (Vitamin-K Antagonist, VKA). El test utiliza sangre capilar fresca. Está indicado para utilizarse en pacientes mayores de 18 años. es The LumiraDx INR Test is a thrombin activation assay in which a quenched substrate is cleaved by thrombin and the emitting fluorescence is detected and quantified. When a blood sample is applied to the Test Strip, the clotting cascade that proceeds naturally leads to the conversion of prothrombin to thrombin which, subsequently, recognizes a peptide sequence on the substrate. Following cleavage of this peptide sequence, the substrate becomes unquenched and emits a fluorescent signal detectable by the LumiraDx Instrument. The amount of signal detected over a specific time is converted by means of an algorithm into standardized coagulation units (INR) and the result is displayed on the touch-screen. en

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