For in vitro diagnostic use. Nucleus Others MSH6 SP93 MMR RxDx-MMR IHC Panel IVD Colorectal Carcinoma VENTANA® anti-MSH6 (SP93) Rabbit Monoclonal Primary Antibody RTD001203 For use with the VENTANA MMR IHC Panel Rabbit SP93 08033676001 MSH6 (SP93) RM PAB-US Export VENTANA anti-MSH6 (SP93) Rabbit Monoclonal Primary Antibody 07613336119365 Reagents, kits 760-5092 50 tests Not Available true 09606769001 MSH6 (SP93) RM PAB W US Export MSH6 (SP93) RM PAB 07613336206195 Reagents, kits 730-7161 Not Available Not Available 09498494001 VENTANA MSH6 (SP93) PAB-US Export J VENTANA MSH6 (SP93) PAB 07613336200223 Reagents, kits 780-7143 Not Available Not Available VENTANA anti-MSH6 (SP93) Rabbit Monoclonal Primary Antibody (VENTANA anti-MSH6 (SP93) antibody) is intended for the qualitative detection of MSH6 protein in formalin-fixed, paraffin-embedded tissue sections. VENTANA- anti- MSH6 (SP93) antibody is ready to use on BenchMark ULTRA, XT and GX instruments with the OptiView DAB IHC Detection Kit and ancillary reagents.VENTANA anti-MSH6 (SP93) antibody is part of the VENTANA MMR IHC Panel which includes VENTANA anti-MLH1 (M1) Mouse Monoclonal Primary Antibody, VENTANA anti-PMS2 (A16-4) Mouse Monoclonal Primary Antibody, VENTANA anti-MSH2 (G219-1129) Mouse Monoclonal Primary Antibody and VENTANA anti-BRAF V600E (VE1) Mouse Monoclonal Primary Antibody.The VENTANA MMR IHC Panel is indicated for the detection of mismatch repair protein deficiency as a test for the identification of individuals at risk for Lynch syndrome in patients diagnosed with colorectal cancer (CRC), and, with BRAF V600E status, as an aid to differentiate between sporadic and probable Lynch syndrome CRC in the absence of MLH1 protein expression.These products should be interpreted by a qualified pathologist in conjunction with histological examination, relevant clinical information, and proper controls.This antibody is intended for in vitro diagnostic (IVD) use. en The VENTANA anti-MSH6 (SP93) antibody is a rabbit monoclonal antibody produced against a synthetic peptide corresponding to an internal region of human MSH6 protein. The VENTANA anti-MSH6 (SP93) antibody binds to MSH6 protein in FFPE tissue sections. The antibody can be localized using a haptenated secondary antibody followed by a multimer anti-hapten-HRP conjugate (OptiView DAB IHC Detection Kit, Cat. No. 760- 700 / 06396500001). The specific antibody-enzyme complex is then visualized with a precipitating enzyme reaction product. Each step is incubated for a precise time and temperature. At the end of each incubation step, the BenchMark ULTRA instrument washes the sections to stop the reaction and to remove unbound material that would hinder the desired reaction in subsequent steps. It also applies ULTRA LCS (Predilute), (Cat. No. 650-210 / 05424534001) or LCS (Predilute) (Cat. No. 650-010 / 05264839001), which minimizes evaporation of the aqueous reagents from the specimen slide.  en