uPath HER2 Dual ISH Image Analysis, Breast RUO

uPath image analysis algorithms

An intelligent and advanced digital pathology solution requires tools that provide pathologists with confident and objective whole tissue slide image analysis. The uPath HER2 Dual ISH image analysis, Breast RUO algorithm aids pathologists in the calculation of HER2/Chromosome 17 ratio by enumeration of the HER2 gene and Chromosome17 signals, in formalin-fixed, paraffin-embedded neoplastic breast tissue specimens.

Roche uPath HER2 Dual ISH image analysis, Breast RUO features

Pathologist-trained artificial intelligence algorithm: Resulting in objective and reproducible scoring of VENTANA DP 200 slide scanner slide images stained with the VENTANA HER2 Dual ISH DNA Probe Cocktail assay
Leveraging Roche uPath enterprise software: Seamless viewing, aligning and syncing functionality, sharing capabilities, and reporting
Whole slide analysis (WSA): Automated pre-computing of the slide image prior to pathologist assessment, providing fast results for user-defined regions of interest (ROI)
Quick automated scoring: Quickly calculates HER2/Chr17 ratio

Heatmap: Intended to guide pathologists to areas ideal for scoring based on an increase of HER2 signals relative to Chr17 signals

Clear visual overlay: Highlighting the 20 representative cells in red
ROI panel: Allowing pathologists to select individual cells and see the corresponding number of HER2 and Chr17 signals

Integrated and ready-to-use

Validated on VENTANA HER2 Dual ISH DNA Probe Cocktail assay, for use within Roche uPath enterprise software.

Quick and automated

Pathologist-trained artificial intelligence algorithm for quick image analysis.

Accurate, consistent and confident

Actionable assessment of scanned slide images that are objective and reproducible.

For Research Use Only. Not for use in diagnostic procedures.