uPath HER2 Dual ISH image analysis, Breast

Ready-to-use, fast, consistent and automated algorithm

uPath-HER2-Dual ISH-product-image

uPath image analysis algorithms


An intelligent and insightful digital pathology solution requires image analysis tools that empower pathologists to confidently and objectively assess whole tissue slide images.


uPath HER2 Dual ISH image analysis, Breast features


  • Pathologist trained: Resulting in objective and reproducible scoring of VENTANA DP 200 slide images stained with the VENTANA HER2 Dual ISH DNA Probe Cocktail assay
  • Leveraging uPath software: Seamless viewing, aligning and syncing functionality, sharing capabilities, and reporting
  • Whole slide analysis (WSA): Automated pre-computing of the slide image prior to pathologist assessment, providing fast results for user-defined regions of interest (ROI)
  • One-click automated scoring: Quickly calculates HER2/Chr17 ratio
uPath-HER2-Dual ISH-product-heatmap
  • Heatmap: Intended to guide pathologists to areas ideal for scoring based on an increase of HER2 signals relative to Chr17 signals
uPath HER2 ISH ROI Panel
  • Clear visual overlay: Highlighting the 20 representative cells in red

  • ROI panel: Allowing pathologists to select individual cells and see the corresponding number of HER2 and Chr17 signals

Integrated and ready-to-use

Validated on VENTANA HER2 Dual ISH DNA Probe Cocktail assay, for use within Roche uPath enterprise software

Quick and automated

Pathologist trained algorithm for one-click image analysis

Accurate, consistent and confident

Actionable assessment of scanned slide images that are objective and reproducible


For research use only. Not for use in diagnostic procedures.