For Research Use Only. Not for use in diagnostic procedures. Others UC-TIB-CPO RUO UC-TIB-CPO 100 1377683945183 This product is not a Roche product, Roche Global Customer Support is not offering any Support. For any additional information and support please ONLY contact TIB MolBiol directly. Furthermore we can not guarantee that all available information for this product is up to date. PID00001076 10 356 839 001 10356839001 UC-TIB-CPO UC-TIB-CPO Reagents, kits 192 reactions Not Available false UC-TIB-CPO is an automated qualitative in vitro test for the detection of CPO DNA. The test utilizes amplification of target DNA by RT-PCR and nucleic acid hybridization for the detection of KPC, OXA48-like, VIM, IMP and NDM genes. en The limit of detection (LoD) for UC-TIB-CPO was determined by analysis of serial dilutions of plasmid DNA in cobas® PCR media (400 μL sample volume). The study demonstrates that the UC-TIB-CPO detects at least 65 genome equivalent copies or less per mL for KPC, 40 copies or less per mL for OXA48-like, 94 copies or less per mL for VIM or IMP and 47 copies or less per mL for NDM, determined by LOGIT analysis with a hit rate of 95%. As of March 2025, the Beta-Lactamase DataBase (BLDB) lists 245 KPC, 67 OXA48-like, 106 IMP, 92 VIM and 78 NDM variants, based on in-silico analysis each of these variants could be detected. The sensitivity for some variants may vary! Some Alcaligenes Faecalis Metallo-β-lactamase (AFM) gene variants might be detected in channel 04, because AFMs are genetically closely related to NDM. en Bacterial DNA is analyzed by real-time PCR that amplifies a 145 bp long fragment of the KPC gene, in channel 01 using a Coumarin-labelled probe, a 209 bp long fragment of the OXA48-like gene, in channel 02 using a FAM-labelled probe, a 149 bp long fragment of the VIM gene and a 184 bp long fragment of the IMP gene, in channel 03 using HEX-labelled probes and a 163 bp long fragment of the NDM gene, in channel 04 using a LC640 labelled probe for the detection of CPO. en

User profile

Select your user profile

UC-TIB-CPO

Overview

Ordering information

Technical documents

Access important product documentation including relevant certificates and other resources.

Compatible products

Related products