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For Research Use Only. Not for use in diagnostic procedures. Others UC-TIB-Factor II V RUO UC-TIB-Factor II/V 100 1377683945183 This product is not a Roche product, Roche Global Customer Support is not offering any Support. For any additional information and support please ONLY contact TIB MolBiol directly.
Furthermore we can not guarantee that all available information for this product is up to date. PID00000863 10 330 244 001 10330244001 UC-TIB-Factor II/V UC-TIB-Factor II/V Reagents, kits 192 reactions Not Available false UC-TIB-Factor II/V allows the detection of Factor II (FII, prothrombin, OMIM 176930) G20210A mutation (NCBI dbSNP: rs1799963) and 'Factor V Leiden' (FV, (OMIM: 612309) G1691A mutation (NCBI dbSNP: rs6025) in genomic human DNA extracted from peripheral blood.
The coagulation Factor V encodes a 330-kD plasma glycoprotein with little or no activity. This precursor is activated by cleavage by thrombin (Factor II). The activated Factor Va is an essential protein in the coagulation pathway and acts as a cofactor for Factor X in the conversion of prothrombin to thrombin. Activated Factor Va itself is inactivated by Activated Protein C. en This assay detects at least 1000 genome equivalent copies or less per mL (plasmid DNA dilution). LoD not tested. en