BenchMark ULTRA IHC/ISH System

This fully automated instrument offers 30 independent slide drawers and single-piece workflow - supporting the largest menu of 250+ ready-to-use assays.

IVD For in vitro diagnostic use.
BenchMark ULTRA IHC/ISH System

True continuous-access automated IHC/ISH slide
staining for unprecedented workflow efficiency

The BenchMark ULTRA IHC/ISH System

Unprecedented workflow

IHC, ISH, SISH, Dual Stain and FITC slides can be processed simultaneously, improving turnaround times. The fully automated workflow enables processing of 90 slides in 8 hours, or 120 slides with an overnight run.


Real-time remote monitoring and technical assistance

The BenchMark ULTRA system is equipped with CareGiver remote monitoring technology, offering 24/7 online support for basic troubleshooting and technical guidance. This provides proactive instrument service and maintenance, helping expedite recovery times to minimize system downtime.

BenchMark ULTRA instrument benefits

Studies have shown that single piece workflow improves laboratory operational efficiencyand the BenchMark ULTRA system - with its thirty independent slide drawers - helps to optimize laboratory workflow by giving histotechnologists continuous access to slide drawers. Single piece workflow maximizes both instrument capacity and laboratory throughput as it eliminates the need to batch samples. Single piece workflow also provides the flexibility to add time-sensitive slides to any available drawer throughout the day without disrupting staining runs in process.

Fully automated

  • Standardized IHC and ISH staining
  • Improve quality, workflow and testing efficiency


  • Individually controlled slide heater pads enable users to run any assay side-by-side
  • Customize time and temperature protocols for each individual slide position

Optimal quality

  • Individual slide heaters, liquid coverslip and air vortex mixers provide an optimal puddle staining environment
  • Sensitive detection chemistries and a broad portfolio of ready-to-use assays 


  • Optimize throughput capacity with single piece workflow
  • Increase laboratory productivity and reduce re-run rates

BenchMark ULTRA instrument features

  • 30 slide positions
  • Ability to add or remove bulk reagents and waste without interrupting cases in process
  • 35 reagent positions
  • Continuous and random slide processing to optimize laboratory workflow
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Workflow features of the BenchMark Ultra


  1. See “Maximizing IHC/ISH capacity and throughput with continuous access and single piece flow” (2016 Australian laboratories study) and “Maximizing capacity and throughput with continuous flow” (2014 United States laboratories study).


Ordering Information

Technical Documents

General characteristics

  • Fully automated

    Baking, deparaffinization, cell conditioning and staining, including IHC, ISH, SISH, immunofluorescence, multiparameter IHC staining (dual, triple), counter stain and titration

  • Slide position

    1–30 slides with independent processing/functionality and temperature control for each position

  • Reagent carousel

    35 reagent positions

  • Slides

    25 x 75 mm, 1 x 3 in or 26 x 76 mm positively charged slides

  • Bulk solutions

    Up to 7 different bulk solutions can be changed “on the fly” without process interruption

  • Waste

    Two 20 L carboys, can be changed “on the fly” without process interruption

  • DI water supply

    NCCLS Type II water or equivalent (deionized water)

  • Temperature control

    Ambient to 100°C

  • Modularity

    One to eight VENTANA BenchMark ULTRA, VENTANA Discovery ULTRA or VENTANA BenchMark Special Stains instruments may be controlled from one BenchMark ULTRA computer system

  • Configuration

    Free standing

  • Certifications

    EC/EN 61010-1, IEC/EN 61010-2-010, IEC/EN 61010-2-101, IEC/EN 61010-2-081, EN 61326-2-6

  • Catalog number

    N750-BMKU-FS 05342716001

Environmental requirements

  • BTU/Hour output

    400 BTU/Hr idle, 1000 BTU/Hr running

  • Room temperature

    68°F to 90°F (20°C to 32°C)

  • Humidity

    10% to 90%, non-condensing

Electrical specifications

  • Voltage


  • Current

    4–6 Amps

  • Frequency

    50/60 Hz

Physical characteristics

  • Size (W x D x H)

    44.00 in x 33.10 in x 62.40 in (111.76 cm x 84.07 cm x 158.50 cm)
    13.5 in x 14.5 in x 13.5 in (34 cm x 37 cm x 34 cm)

  • Weight

    650 lbs (294.8 kg)

  • Clearances

    Top 15 in (38.1 cm)
    Sides 4 in (10.2 cm)
    Rear 6 in (15.2 cm)

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